Clinical Trials

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT02444741 2026-05-15

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Phase 1/2 Completed

124 enrolled 15 charts

Carcinoma, Non-Small-Cell Lung

NCT04671667 2026-05-08

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Phase 2 Recruiting

188 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03180268 2026-05-07

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Phase 3 Recruiting

163 enrolled

Meningioma

NCT03801876 2026-05-07

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Phase 3 Recruiting

300 enrolled

Gastrointestinal

Clinical Stage I Esophageal Adenocarcinoma AJCC v8

NCT01245712 2026-05-01

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

200 enrolled

Breast

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT04946357 2026-04-06

EXTREM ION

42 enrolled

Sarcoma

NCT04894643 2026-03-20

PARC

10 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT04190446 2026-03-16

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

84 enrolled

Phase 1/2 Active not recruiting

Prostatic Neoplasms

NCT01629498 2026-03-09

Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer

146 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04083937 2026-03-09

PAROS

897 enrolled

Phase 3 Active not recruiting

Prostatic Neoplasms

NCT01893307 2026-02-24

Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

440 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04278118 2026-02-17

HiPPI

70 enrolled

CNSEndocrine

Brain Neoplasms, Meningioma, Neurilemmoma, Pituitary Neoplasms, Nerve Sheath Neoplasms

NCT04725903 2026-02-17

Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer

30 enrolled

Phase 3 Active not recruiting

Prostatic Neoplasms

NCT04443413 2026-01-16

Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients

146 enrolled

Breast

Anatomic Stage I Breast Cancer AJCC v8

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

606 enrolled

Phase 1/2 Active not recruiting

Glioblastoma

NCT01950351 2025-12-22

Hypofractionated Proton Beam Therapy for Localized Prostate Cancer

241 enrolled

Stage I Prostate Adenocarcinoma AJCC v7

NCT02314364 2025-12-16

A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC

Phase 2 Completed

27 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03132532 2025-11-25

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Phase 2 Completed

20 enrolled 20 charts

Phase NA Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04656041 2025-11-14

Folfox+Irinotecan+Chemort In Esophageal Cancer

Phase 2 Recruiting

40 enrolled

Gastrointestinal

Gastroesophageal Junction Adenocarcinoma

NCT06008730 2025-11-10

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

Phase 2 Recruiting

20 enrolled

Resectable Lung Non-Small Cell Carcinoma

NCT02603341 2025-11-06

Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

1,238 enrolled

Breast

Breast Neoplasms

NCT00969111 2025-09-09

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

70 enrolled

Prostatic Neoplasms

NCT04342429 2025-07-15

Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer

30 enrolled

Small Cell Lung Carcinoma

NCT03778294 2025-07-03

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

Phase 2 Completed

43 enrolled 19 charts