Clinical Trials

42 enrolled

Sarcoma

NCT03801876 2026-04-03

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Phase 3 Recruiting

300 enrolled

Gastrointestinal

Clinical Stage I Esophageal Adenocarcinoma AJCC v8

NCT04894643 2026-03-20

PARC

10 enrolled

Gastrointestinal

Pancreatic Neoplasms

NCT04190446 2026-03-16

A Study to Evaluate Hypofractionated Proton Therapy or IMRT for Recurrent, Oligometastatic Prostate Cancer

84 enrolled

Phase 1/2 Active not recruiting

Prostatic Neoplasms

NCT01629498 2026-03-09

Image-Guided, Intensity-Modulated Photon or Proton Beam Radiation Therapy in Treating Patients With Stage II-IIIB Non-small Cell Lung Cancer

146 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04083937 2026-03-09

PAROS

897 enrolled

Phase 3 Active not recruiting

Prostatic Neoplasms

NCT01893307 2026-02-24

Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

440 enrolled

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT04278118 2026-02-17

HiPPI

70 enrolled

CNSEndocrine

Brain Neoplasms, Meningioma, Neurilemmoma, Pituitary Neoplasms, Nerve Sheath Neoplasms

NCT04725903 2026-02-17

Proton Radiation Therapy for the Treatment of Patients With High Risk Prostate Cancer

30 enrolled

Phase 3 Active not recruiting

Prostatic Neoplasms

NCT04443413 2026-01-16

Phase III Study of 5tx vs 15tx of RT (X-rays or Protons) Including RNI in Breast Cancer Patients

146 enrolled

Breast

Anatomic Stage I Breast Cancer AJCC v8

NCT02179086 2026-01-14

Dose-Escalated Photon IMRT or Proton Beam Radiation Therapy Versus Standard-Dose Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

606 enrolled

Glioblastoma

NCT03180268 2026-01-14

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Phase 3 Recruiting

163 enrolled

Phase 1/2 Active not recruiting

Meningioma

NCT01950351 2025-12-22

Hypofractionated Proton Beam Therapy for Localized Prostate Cancer

241 enrolled

Stage I Prostate Adenocarcinoma AJCC v7

NCT01245712 2025-12-17

Radiation Therapy in Treating Patients With Stage 0-II Breast Cancer

200 enrolled

Breast

Breast Carcinoma In Situ, Breast Neoplasms, Carcinoma, Intraductal, Noninfiltrating

NCT02314364 2025-12-16

A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC

Phase 2 Completed

27 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT03132532 2025-11-25

Platinum Doublet Chemotherapy and Proton Beam Radiation Therapy in Treating Patients With Stage II-III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Phase 2 Completed

20 enrolled 20 charts

Phase NA Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04656041 2025-11-14

Folfox+Irinotecan+Chemort In Esophageal Cancer

Phase 2 Recruiting

40 enrolled

Gastrointestinal

Gastroesophageal Junction Adenocarcinoma

NCT06008730 2025-11-10

Proton Beam Radiation Therapy After Treatment for Resected N2 Non-Small Cell Lung Cancer

Phase 2 Recruiting

20 enrolled

Resectable Lung Non-Small Cell Carcinoma

NCT02603341 2025-11-06

Pragmatic Randomized Trial of Proton vs. Photon Therapy for Patients With Non-Metastatic Breast Cancer: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

1,238 enrolled

Breast

Breast Neoplasms

NCT02444741 2025-10-09

Pembrolizumab and Stereotactic Body Radiation Therapy or Non-Stereotactic Wide-Field Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Phase 1/2 Active not recruiting

126 enrolled

Carcinoma, Non-Small-Cell Lung

NCT00969111 2025-09-09

Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy

70 enrolled

Prostatic Neoplasms

NCT04342429 2025-07-15

Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer

30 enrolled

Small Cell Lung Carcinoma

NCT03180502 2025-07-11

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

120 enrolled

Astrocytoma, Glioma, Oligodendroglioma

NCT03778294 2025-07-03

18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy

Phase 2 Completed

43 enrolled 19 charts