Clinical Trials

Carcinoma, Non-Small-Cell Lung

NCT04929223 2026-05-26

A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

Phase 1 Recruiting

542 enrolled

Colorectal Neoplasms

NCT04524871 2026-05-22

MORPHEUS-LIVER

Phase 1/2 Recruiting

518 enrolled

Advanced Liver Cancers

NCT03337698 2026-05-12

Morpheus Lung

Phase 1/2 Terminated

314 enrolled 31 charts

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT05805501 2026-05-12

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

199 enrolled

Genitourinary

Carcinoma, Renal Cell

NCT05862285 2026-05-12

UmbrellaMAX

Phase 3 Recruiting

100 enrolled

Tumor-Agnostic

Neoplasms

NCT04665843 2026-05-05

SKYSCRAPER-09

123 enrolled 22 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT03563716 2026-05-04

A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

135 enrolled 19 charts

Phase 2 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT05645692 2026-04-29

A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer

204 enrolled

Genitourinary

Urothelial Cancer

NCT05009069 2026-04-21

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

Phase 2 Active not recruiting

58 enrolled

Phase 3 Active not recruiting

Rectal Neoplasms

NCT04543617 2026-04-17

SKYSCRAPER-07

760 enrolled

Esophageal Squamous Cell Carcinoma

NCT04540211 2026-04-09

SKYSCRAPER-08

461 enrolled 24 charts

Esophageal Neoplasms

NCT04256421 2026-04-03

SKYSCRAPER-02

490 enrolled 33 charts

Small Cell Lung Carcinoma

NCT04300647 2026-03-12

SKYSCRAPER-04

172 enrolled 27 charts

Gynecologic

Uterine Cervical Neoplasms

NCT04832854 2026-03-11

A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer

Phase 2 Terminated

50 enrolled 18 charts

Phase 3 Active not recruiting

Carcinoma, Non-Small-Cell Lung

NCT04665856 2026-02-13

SKYSCRAPER-02C

123 enrolled 26 charts

Small Cell Lung Carcinoma

NCT05661578 2026-02-09

SKYSCRAPER-11

64 enrolled

Other solid neoplasm

PD-L1-selected Solid Tumors

NCT06267001 2026-02-03

SKYSCRAPER-15

56 enrolled

Carcinoma, Non-Small-Cell Lung

NCT04294810 2026-01-30

SKYSCRAPER-01

620 enrolled

Carcinoma, Non-Small-Cell Lung

NCT03869190 2026-01-22

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Phase 3 Active not recruiting

272 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT05904886 2025-12-31

SKYSCRAPER-14

687 enrolled

Carcinoma, Hepatocellular

NCT03281369 2025-12-15

A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)

214 enrolled

Esophageal Neoplasms

NCT05908786 2025-12-11

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

62 enrolled

Carcinoma, Hepatocellular

NCT03193190 2025-11-21

A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

341 enrolled 28 charts

Pancreatic Adenocarcinoma

NCT05459129 2025-09-15

A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)

12 enrolled 18 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT05116202 2025-07-18

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)