Announcements Trials
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Phase

Phase 2 3Phase 1/2 1

Status

Withdrawn 1Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

INDUSTRY 12OTHER 4NIH 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 1Sarcoma 1Gastrointestinal 1CNS 1

Conditions

Sarcoma 1Rectal Neoplasms 1Glioma 1Glioblastoma 1Extensive Stage Small Cell Lung Carcinoma 1

Interventions

pembrolizumab 593Cyclophosphamide 539Magnetic Resonance Spectroscopy 527Radiotherapy 506Specimen Handling 504Nivolumab 406Cisplatin 370Carboplatin 360Biopsy 306Blood Specimen Collection 296Radiosurgery 284Paclitaxel 276Surveys and Questionnaires 269Standard of Care 267Gemcitabine 266fludarabine 261Dexamethasone 258Drug Therapy 256Bevacizumab 248venetoclax 247Oxaliplatin 206Rituximab 197Capecitabine 194Radiation 190Fluorouracil 186Ipilimumab 183durvalumab 181Doxorubicin 174atezolizumab 172Etoposide 171

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
OTHER × epacadostat × 1 year × Clear all
NCT03402880 2026-05-29

ALCMI-005: Pembrolizumab and Epacadostat in Treating Patients With Extensive Stage Small Cell Lung Cancer

City of Hope Medical Center

Phase 2 Withdrawn
Thoracic

Extensive Stage Small Cell Lung Carcinoma

NCT03414229 2026-04-23

A Study of Epacadostat, an IDO1 Inhibitor, in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

Memorial Sloan Kettering Cancer Center

Phase 2 Active not recruiting
30 enrolled 11 charts
Sarcoma

Sarcoma

NCT03516708 2026-02-11

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

Washington University School of Medicine

Phase 1/2 Recruiting
49 enrolled
Gastrointestinal

Rectal Neoplasms

NCT03532295 2025-11-21

Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas

Washington University School of Medicine

Phase 2 Completed
51 enrolled 16 charts
CNS

Glioblastoma, Glioma

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