Announcements Trials
Browse Landscape

Phase

Phase 2 1Phase 1/2 1Phase 1 1

Status

Recruiting 2Completed 2Active not recruiting 1

Sponsor Class

INDUSTRY 5OTHER 4NIH 4NETWORK 1

Study Type

Interventional 3Observational 2

Sponsor

Cancer Type

Other solid neoplasm 3Tumor-Agnostic 1Thoracic 1Sarcoma 1Head & Neck 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Neoplasms 2Thyroid Neoplasms 1Solid Tumors Harboring NTRK Fusion 1Sarcoma 1Salivary Gland Neoplasms 1Melanoma 1Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1Biliary Tract Neoplasms 1Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion 1

Interventions

pembrolizumab 604Carboplatin 372Paclitaxel 282Cisplatin 267Gemcitabine 252Pemetrexed 193Bevacizumab 190Docetaxel 185Nivolumab 181Injections 167Cyclophosphamide 147atezolizumab 138Fluorouracil 133Capecitabine 133Oxaliplatin 132Dexamethasone 127Fulvestrant 113durvalumab 112130-nm albumin-bound paclitaxel 110fludarabine 101Cetuximab 100Leucovorin 97Rituximab 94venetoclax 90Lenalidomide 83enzalutamide 77Prednisone 76Azacitidine 74Irinotecan 72Ipilimumab 72

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × larotrectinib × 1 year × Clear all
NCT02576431 2026-04-28

NAVIGATE

Bayer

Phase 2 Completed
215 enrolled 2 FDA
BreastDermatologicGastrointestinalHead & NeckSarcomaThoracic

Biliary Tract Neoplasms, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Salivary Gland Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT04142437 2026-04-14

ON-TRK

Bayer

Recruiting
150 enrolled
Other solid neoplasm

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

NCT04945330 2026-04-14

NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes

Bayer

Recruiting
100 enrolled
Other solid neoplasm

Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion

NCT02122913 2026-02-05

A Study to Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Bayer

Phase 1 Completed
75 enrolled 2 FDA
Other solid neoplasm

Solid Tumors Harboring NTRK Fusion

NCT02637687 2025-06-22

SCOUT

Bayer

Phase 1/2 Active not recruiting
154 enrolled 2 FDA
Tumor-Agnostic

Neoplasms

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