Clinical Trials Browser

Neoplasm Metastasis

Advanced Breast Cancer

Breast Neoplasms

Breast Neoplasms

Breast Neoplasms, Neoplasm Metastasis, Neoplasm, Residual

Breast Neoplasms, Drug-Related Side Effects and Adverse Reactions

Brain Neoplasms, Breast Neoplasms

Breast Cancer Metastatic

Salivary Gland Neoplasms

Breast Neoplasms

Breast Neoplasms

Breast Neoplasms

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

Ovarian Neoplasms, Recurrence

Breast Neoplasms

Gastric Adenocarcinoma

Breast Neoplasms

Breast Neoplasms

Colorectal Neoplasms

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Neoplasms

Colorectal Neoplasms

Brain Neoplasms, Breast Neoplasms

Brain Neoplasms, Glioblastoma, Neoplasm Metastasis, Meningeal Carcinomatosis

Carcinoma, Non-Small-Cell Lung

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

Breast Neoplasms

Carcinoma, Non-Small-Cell Lung

Breast Neoplasms

Breast Neoplasms

Breast Neoplasms

Neoplasm Metastasis, Neoplasms

Stomach Neoplasms

Stomach Neoplasms

Breast Neoplasms

HER2-positive Breast Cancer

Breast Neoplasms

Advanced Breast Cancer

Breast Neoplasms

Breast Neoplasms

Breast Neoplasms, Inflammatory Breast Neoplasms

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

Breast Cancer With Brain Metastasis

Breast Neoplasms

Breast Cancer With Brain Metastasis

Breast Neoplasms

Breast Neoplasms

HER2 Overexpression

Brain Neoplasms, Breast Neoplasms, Neoplasm Metastasis, Meningeal Carcinomatosis

Clinical Trials

Dose-Escalation and Dose-Expansion Study of BSI-082 Monotherapy and Combined Therapy in Patients With Advanced or Metastatic Solid Tumors

PONTIAC

Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer

HEROIC

HER2 CR

Impact of Genetic Variants on the Toxicity of Antibody-Drug Conjugates in Locally Advanced or Metastatic Breast Cancer: The Role of the UGT1A1 Gene as a Predictive Biomarker of Therapeutic Response

TUXEDO-4

Trial of Trastuzumab Deruxtecan in Previously Treated HER2

Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

DEMETHER

Phase 1b Study Of TRICK-NK In Combination With T-Dxd In Treatment-Refractory Breast Cancers

MEGA-TACT-BC3

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

TROY

ERADICATE

Phase 2 Study of Trastuzumab Deruxtecan in the Neoadjuvant Treatment, or Trastuzumab Deruxtecan Plus Capecitabine Plus Durvalumab(MEDI4736) in the Preoperative and Postoperative Adjuvant Treatment for Patients With HER2 Positive Gastric and Gastroesophageal Junction Adenocarcinoma

TRANSCENDER

TOP-REAL

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Trastuzumab Deruxtecan + Stereotactic Radiosurgery (SRS) in HER2+ Breast Cancer Brain Metastases

ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer

An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer

HERCULES

CHIMERA

DISCORDANT

ELPIS

Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer

STORM

Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer

Trastuzumab Deruxtecan to Treat HER2 + Newly Diagnosed Metastatic GI Cancers

Trastuzumab Deruxtecan(T-DXd) and Afatinib Combination in HER2-low Advanced Gastric Cancer

Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

ANISE

Scalp Cooling in MBC

ADAPTHER2-IV

Trastuzumab Deruxtecan in Advanced Breast Cancer

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

TRADE DXd

TRUDI

Safety and Efficacy Real-world Data of Trastuzumab Deruxtecan and Sacituzumab Govitecan

ALTER

THUNDER

ARIADNE

THUMB

INOVATE

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

A Real-world Clinical Study of T-DXd for the Treatment of Chinese Patients With HER2 Overexpressing and HER2 Underexpressing Advanced Breast Cancer

DEBBRAH