NCT05050084 2026-04-08Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance TrialNRG OncologyPhase 3 Active not recruiting2,050 enrolled
NCT04423211 2026-04-03Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET ImagingEastern Cooperative Oncology GroupPhase 3 Recruiting804 enrolled
NCT04513717 2026-04-03Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT TrialNRG OncologyPhase 3 Active not recruiting2,753 enrolled
NCT04484818 2026-03-23Testing the Addition of Darolutamide to Hormonal Therapy (Androgen Deprivation Therapy [ADT]) After Surgery for Men With High-Risk Prostate Cancer, The ERADICATE StudyEastern Cooperative Oncology GroupPhase 3 Active not recruiting27 enrolled