Clinical Trials Browser

Breast Neoplasms

NCT04248582 2026-04-15

Cryotherapy for Locally Advanced Esophageal Cancer

Phase 1 Active not recruiting

14 enrolled

Gastrointestinal

Esophageal Neoplasms

NCT04693377 2026-04-15

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Phase NA Recruiting

40 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

NCT03546686 2026-03-27

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

Phase 2 Active not recruiting

51 enrolled

Breast

Breast Neoplasms

NCT07398118 2026-03-23

CRYO-1

Phase NA Not yet recruiting

61 enrolled

Breast

Breast Neoplasms

NCT07450352 2026-03-04

SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors

Phase 2 Not yet recruiting

150 enrolled

Other solid neoplasm

Unresectable Solid Tumors

NCT07437625 2026-02-27

Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease

Phase 2 Not yet recruiting

90 enrolled

Other solid neoplasm

High-Burden Metastatic Solid Tumors

NCT07439432 2026-02-27

Stereotactic Guided Biopsy and Cryoablation

Phase NA Withdrawn

Breast

Breast Neoplasms

NCT07416448 2026-02-18

NAP-C/R

Phase NA Recruiting

50 enrolled

Agnosia, Hypesthesia, Neuralgia, Neuroma

NCT04150939 2026-02-17

Cryoablation for the Treatment of Metastatic Cancer

Phase NA Active not recruiting

15 enrolled

Tumor-Agnostic

Neoplasm Metastasis

NCT06593106 2026-02-02

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

Phase NA Recruiting

30 enrolled

Thoracic

Lung Neoplasms

NCT04339218 2026-01-30

CRYOMUNE

Phase 3 Recruiting

214 enrolled

Thoracic

Adenocarcinoma of Lung

NCT04701918 2026-01-22

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Phase 2 Completed

9 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT07232433 2026-01-22

Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules

Phase NA Recruiting

90 enrolled

Thoracic

Lung Neoplasms

Clinical Trials

LUBRECA

Cryotherapy for Locally Advanced Esophageal Cancer

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

CRYO-1

SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors

Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease

Stereotactic Guided Biopsy and Cryoablation

NAP-C/R

Cryoablation for the Treatment of Metastatic Cancer

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

CRYOMUNE

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules