Clinical Trials Browser

Phase 2 × Metformin × 90 days × Clear all

NCT02365597 2026-06-05

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Phase 2 Active not recruiting

239 enrolled 32 charts 1 FDA

Urothelial Cancer

NCT07226453 2026-06-05

PNOC041

Phase 2 Recruiting

Posterior Fossa Ependymal Tumor

NCT02186847 2026-05-22

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

Phase 2 Completed

170 enrolled 19 charts

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung

NCT07604870 2026-05-22

Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity

Phase 2 Completed

Obesity, Polycystic Ovary Syndrome

NCT04414540 2026-05-08

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

Phase 2 Active not recruiting

21 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck

NCT04742751 2026-04-30

An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

Phase 2 Active not recruiting

Prediabetic State

NCT04114136 2026-04-24

Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

Phase 2 Recruiting

DermatologicGastrointestinalHead & Neck

Adenocarcinoma Of Esophagus, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Hepatocellular, Melanoma

NCT02874430 2026-04-22

Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

Phase 2 Terminated

29 enrolled 11 charts

Breast Neoplasms

NCT05237960 2026-04-20

Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

Phase 2 Active not recruiting

Erythroplasia, Leukoplakia, Oral

NCT02581137 2026-04-13

Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

Phase 2 Active not recruiting

26 enrolled 10 charts

Erythroplasia, Hyperplasia, Leukoplakia, Oral, Mouth Neoplasms

NCT02437656 2026-03-31

METCAP

Phase 2 Completed

Gastrointestinal

Rectal Neoplasms

NCT02122185 2026-03-27

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Phase 2 Completed

111 enrolled 15 charts

GynecologicThoracic

Carcinoma, Ovarian Epithelial, Brenner Tumor, Fallopian Tube Neoplasms, Pleural Effusion, Malignant