NCT06130254 2026-04-09Phase Ib Trial of the KRAS G12C Inhibitor Adagrasib (MRTX849) in Combination With the PARP Inhibitor Olaparib in Patients With KRAS G12C Mutated Advanced Solid Tumors, With a Focus on Gynecological, Breast, Pancreatic and KEAP1 Mutated Non-small Cell Lung CancersM.D. Anderson Cancer CenterPhase 1 Terminated1 enrolled
NCT05722327 2026-03-04Phase I Trial of Adagrasib (MRTX849) in Combination With Cetuximab and Irinotecan in Patients With Colorectal CancerM.D. Anderson Cancer CenterPhase 1 Active not recruiting24 enrolled
NCT07382726 2026-02-20Phase 1 Study Of Izalontamab Brengitecan + Adagrasib In NSCLC - The IZA-A TrialM.D. Anderson Cancer CenterPhase 1 Not yet recruiting18 enrolled
NCT05578092 2026-02-19A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK PathwayMirati Therapeutics Inc.Phase 1 Terminated64 enrolled