NCT07006688 2026-04-06A Study of an IDH1m Inhibitor in Participants With IDH1-Mutated Malignancies and Hepatic or Renal ImpairmentServierPhase 1 Recruiting30 enrolled
NCT02677922 2026-02-19A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction ChemotherapyCelgenePhase 1/2 Active not recruiting130 enrolled 38 charts
NCT02073994 2026-02-17Study of Orally Administered AG-120 in Subjects With Advanced Solid Tumors, Including Glioma, With an IDH1 MutationServierPhase 1 Completed174 enrolled
NCT03343197 2026-02-17Study of AG-120 and AG-881 in Subjects With Low Grade GliomaServierPhase 1 Completed49 enrolled