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NCT00804856 2023-10-03

Phase I/IIa Trial to Investigate BI 6727 (Volasertib) as Monotherapy or in Combination With Cytarabine in Acute Myeloid Leukaemia

Phase 2 Completed

180 enrolled 44 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02273388 2023-10-03

BI 6727 Administered Intravenously Every 3 Weeks in Patients With Solid Tumours

Phase 1 Completed

65 enrolled 42 charts

Neoplasms

NCT01772563 2023-09-01

Investigation of Potential Drug-drug Interaction of Volasertib With Itraconazole in Patients With Various Tumours

Phase 1 Completed

28 enrolled 10 charts

Neoplasms

NCT01721876 2023-02-08

Volasertib in Combination With Low-dose Cytarabine in Patients Aged 65 Years and Above With Previously Untreated Acute Myeloid Leukaemia, Who Are Ineligible for Intensive Remission Induction Therapy (POLO-AML-2)

Phase 3 Completed

666 enrolled 14 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT00969553 2019-07-26

Dose Finding Study of BI 6727 (Volasertib) in Patients With Various Solid Cancers

Phase 1 Completed

59 enrolled 28 charts

Neoplasms

NCT01957644 2019-02-08

Phase I Dose Escalation Trial of Volasertib in Combination With Azacitidine in Patients With MDS or CMML

Phase 1 Terminated

16 enrolled 9 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT01206816 2019-02-01

An Open Label Phase I Dose Escalation Trial of Intravenous BI 6727 (Volasertib)in Combination With Oral BIBW 2992 (Afatinib) in Patients With Advanced Solid Tumours

Phase 1 Completed

57 enrolled 19 charts

Neoplasms

NCT00969761 2019-01-31

BI 6727 (Volasertib) in Combination With Cisplatin or Carboplatin in Patients With Advanced or Metastatic Solid Tumour

Phase 1 Completed

61 enrolled 40 charts

Neoplasms

NCT01145885 2019-01-31

BI 6727 (Volasertib) Human ADME Trial in Various Solid Tumours

Phase 1 Completed

7 enrolled 22 charts

Neoplasms

NCT01348347 2018-08-06

BI 6727 (Volasertib) Monotherapy Phase I Trial in Japanese Patients With Advanced Solid Tumours

Phase 1 Completed

15 enrolled 12 charts

Neoplasms

NCT01022853 2018-07-30

Combination of BI6727 (Volasertib) and BIBF1120 in Solid Tumors

Phase 1 Completed

30 enrolled 24 charts

Neoplasms

NCT01662505 2018-07-30

Volasertib in Japanese Patients With Acute Myeloid Leukemia (AML)

Phase 1 Completed

19 enrolled 13 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT01971476 2018-07-30

Open Dose Escalating Trial to Determine the Maximum Tolerated Dose in Paediatric Patients With Advanced Cancers for Whom no Therapy is Known

Phase 1 Completed

22 enrolled 14 charts

Other hematologic neoplasm

Leukemia, Neoplasms

NCT02201329 2018-07-30

Volasertib in Combination With Azacitidine in Japanese Patients With Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Phase 1 Completed

5 enrolled 9 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT01023958 2017-11-22

Intravenous BI 6727 (Volasertib) in 2nd Line Treatment of Urothelial Cancer

Phase 2 Completed

50 enrolled 29 charts

Neoplasms

NCT00824408 2016-09-20

Trial of BI 6727 (Volasertib) Monotherapy and BI 6727 in Combination With Pemetrexed Compared to Pemetrexed Monotherapy in Advanced NSCLC

Phase 2 Completed

143 enrolled 23 charts

Carcinoma, Non-Small-Cell Lung

NCT01121406 2015-08-13

BI 6727 (Volasertib) Randomised Trial in Ovarian Cancer

Phase 2 Completed

110 enrolled 32 charts

Ovarian Neoplasms