Clinical Trials

Stomach Neoplasms

NCT03221426 2026-03-09

KEYNOTE-585

1,007 enrolled 25 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT04882241 2026-03-06

KEYNOTE-585

120 enrolled 17 charts

Phase 3 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT04494425 2026-03-04

DB-06

866 enrolled 25 charts 3 FDA

Breast Neoplasms

NCT03523585 2026-02-27

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

608 enrolled 17 charts

Breast Neoplasms

NCT03675737 2026-02-27

KEYNOTE-859

1,579 enrolled 31 charts 2 FDA

Phase 2 Active not recruiting

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT04430738 2026-02-24

Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers

40 enrolled 67 charts

Phase 3 Active not recruiting

Adenocarcinoma Of Esophagus, Esophageal Neoplasms, Gallbladder Neoplasms, Stomach Neoplasms, Colorectal Neoplasms, Cholangiocarcinoma

NCT05104866 2026-02-04

A Phase-3, Open-Label, Randomized Study of Dato-DXd Versus Investigator's Choice of Chemotherapy (ICC) in Participants With Inoperable or Metastatic HR-Positive, HER2-Negative Breast Cancer Who Have Been Treated With One or Two Prior Lines of Systemic Chemotherapy (TROPION-Breast01)

732 enrolled 22 charts 3 FDA

Phase 2 Active not recruiting

Breast Neoplasms, Neoplasm Metastasis

NCT04721977 2026-01-09

MK-7119-001

66 enrolled 7 charts

Breast Neoplasms

NCT03615326 2025-12-11

MK-3475-811

738 enrolled 22 charts 7 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT04428151 2025-12-04

LEAP-009

408 enrolled 17 charts

Head & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck

NCT03371017 2025-11-12

IMpassion132

595 enrolled 37 charts

Triple Negative Breast Neoplasms

NCT04363801 2025-10-09

DisTinGuish

Phase 2 Terminated

247 enrolled 38 charts

Phase 3 Active not recruiting

Adenocarcinoma, Neoplasms, Stomach Neoplasms

NCT03734029 2025-10-06

Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]

557 enrolled 22 charts 2 FDA

Breast Neoplasms, Neoplasm Metastasis

NCT04047862 2025-08-22

Study of Ociperlimab (BGB-A1217) in Combination With Tislelizumab in Advanced Solid Tumors

Phase 1 Completed

446 enrolled 49 charts

Other solid neoplasm

Locally Advanced and Metastatic Solid Tumors

NCT00680901 2025-08-07

LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus Lapatinib

545 enrolled 24 charts

Esophageal Neoplasms, Neoplasm Metastasis, Neoplasms

NCT02872116 2025-08-07

CheckMate649

2,031 enrolled 19 charts 2 FDA

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT03783442 2025-07-29

A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

649 enrolled 22 charts

Esophageal Squamous Cell Carcinoma

NCT02795988 2025-04-16

A Study of IMU-131(HER-Vaxx) and Chemotherapy Compared to Chemotherapy Only in Patients With HER2 Positive Advanced Gastric Cancer

Phase 1/2 Completed

64 enrolled 20 charts

Adenocarcinoma, Gastrointestinal Neoplasms, Neoplasm Metastasis

NCT02780700 2025-02-03

Nintedanib Alone or in Combination With Capecitabine in Refractory Metastatic Colorectal Cancer [LUME-Colon 2]

Phase 2 Terminated

1 enrolled 5 charts

Colorectal Neoplasms

NCT03329248 2024-12-12

QUILT-3.060: NANT Pancreatic Cancer Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

6 enrolled 15 charts

Pancreatic Neoplasms

NCT03563157 2024-12-11

QUILT 3.071: NANT Colorectal Cancer (CRC) Vaccine

2 enrolled 13 charts

Colorectal Neoplasms

NCT03009058 2024-11-25

MODULATE

2 enrolled 7 charts

DermatologicSarcoma

Melanoma, Neoplasm Metastasis, Sarcoma

NCT03512756 2024-11-06

A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer

Phase 2/3 Terminated

130 enrolled 13 charts

Neoplasm Metastasis, Neoplasms, Pancreatic Neoplasms

NCT04456699 2024-10-29

LYNK-003

335 enrolled 19 charts

Colorectal Neoplasms

NCT03901339 2024-10-21

TROPiCS-02

543 enrolled 25 charts 2 FDA

Breast Neoplasms

NCT03839823 2024-10-09

RIGHT Choice

222 enrolled 17 charts

Breast Neoplasms

NCT03586869 2024-08-27

QUILT-3.080: NANT Pancreatic Cancer Vaccine

3 enrolled 13 charts

Pancreatic Neoplasms

NCT02743221 2024-08-20

TASCO1

154 enrolled 15 charts

Neoplasm Metastasis, Neoplasms, Colorectal Neoplasms

NCT03387085 2024-08-09

QUILT-3.067: NANT Triple Negative Breast Cancer (TNBC) Vaccine: Molecularly Informed Integrated Immunotherapy in Subjects With TNBC Who Have Progressed on or After Standard-of-care Therapy.

9 enrolled 18 charts

Triple Negative Breast Neoplasms

NCT03387111 2024-08-05

QUILT-3.090: NANT Squamous Cell Carcinoma (SCC) Vaccine: Subjects With SCC Who Have Progressed

4 enrolled 14 charts

Tumor-Agnostic

Carcinoma, Squamous Cell

NCT03136406 2024-06-11

QUILT-3.039: NANT Pancreatic Cancer Vaccine: Combination Immunotherapy in Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

3 enrolled 9 charts

Pancreatic Neoplasms

NCT03387098 2024-05-22

QUILT-3.070:Pancreatic Cancer Vaccine: Subjects With Pancreatic Cancer Who Have Progressed on or After Standard-of-care Therapy

4 enrolled 9 charts

Pancreatic Neoplasms

NCT02291289 2024-05-06

MODUL

1,044 enrolled 21 charts

Colorectal Neoplasms

NCT03887130 2024-04-30

Study of Oral Vinorelbine Plus Capecitabine Versus Taxane-gemcitabine Combinations as 1st Line Chemotherapy in Metastatic Breast Cancer

152 enrolled 14 charts

Breast Neoplasms

NCT03472365 2024-01-11

A Study of SHR-1210 in Combination With Capecitabine + Oxaliplatin or Apatinib in Treatment of Advanced Gastric Cancer

67 enrolled 12 charts

Stomach Neoplasms

NCT01776307 2023-11-15

A Study of BBI608 in Adult Patients With Advanced Colorectal Cancer

200 enrolled 23 charts

Colorectal Neoplasms

NCT02024607 2023-11-15

A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer

Phase 1/2 Completed

495 enrolled 18 charts

Advanced Gastrointestinal Cancer

NCT03262935 2023-10-19

TULIP

437 enrolled 17 charts

Breast Neoplasms

NCT02614794 2023-08-14

HER2CLIMB

612 enrolled 30 charts 3 FDA

BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT02611960 2023-07-13

Keynote-122

233 enrolled 21 charts

Head & Neck

Parkinson Disease 4, Autosomal Dominant Lewy Body, Nasopharyngeal Neoplasms

NCT01439282 2023-06-22

Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer

77 enrolled 9 charts

Breast Neoplasms

NCT02494583 2023-04-13

MK-3475-062

763 enrolled 29 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT03770689 2023-03-21

Study of Peposertib in Combination With Capecitabine and RT in Rectal Cancer

Phase 1/2 Completed

19 enrolled 21 charts

Locally Advanced Rectal Cancer

NCT04366713 2023-02-10

A Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib

6 enrolled 8 charts

Breast Neoplasms

NCT05091528 2022-08-18

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

BreastGastrointestinalThoracic

2 enrolled 9 charts

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms, Colorectal Neoplasms

NCT02335411 2022-08-08

KEYNOTE-059

318 enrolled 24 charts 2 FDA

NCT02574455 2022-06-15

ASCENT

529 enrolled 23 charts 2 FDA

Breast Neoplasms

NCT02625610 2022-06-09

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)