Clinical Trials Browser

Terminated × Has results × Decitabine × Clear all

NCT05799079 2026-01-09

Decitabine and Cedazuridine in Combination With Venetoclax for the Treatment of Patients Who Have Relapsed Acute Myeloid Leukemia After Donor Stem Cell Transplant

Phase 2 Terminated

1 enrolled 8 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT05918055 2025-12-02

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Phase 1/2 Terminated

3 enrolled 9 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT05148234 2025-09-30

BMS-986253 in Myelodysplastic Syndromes

Phase 1/2 Terminated

2 enrolled 11 charts

Classical hematologyMyeloid

Cytopenia, Myelodysplastic Syndromes

NCT02608268 2023-12-06

Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

Phase 1/2 Terminated

252 enrolled 67 charts

DermatologicGenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Melanoma

NCT03593915 2023-11-09

A Phase 1b/2 Study of Alvocidib Plus Decitabine or Azacitidine in Patients With MDS

Phase 1/2 Terminated

20 enrolled 13 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Neoplasms, Leukemia, Myelomonocytic, Chronic

NCT03233724 2023-05-31

Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas

Phase 1/2 Terminated

9 enrolled 14 charts

GastrointestinalOther solid neoplasmThoracic

Mesothelioma, Malignant, Carcinoma, Non-Small-Cell Lung, Esophageal Neoplasms, Lung Neoplasms

NCT03063203 2022-06-02

Single Agent Decitabine in TP53 Mutated Relapsed/Refractory Acute Myeloid Leukemia

Phase 2 Terminated

17 enrolled 20 charts

Other hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

NCT04051996 2021-10-15

GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia

Phase 2 Terminated

1 enrolled 4 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT03113071 2021-03-16

Safety and Activity of Digoxin With Decitabine in Adult AML and MDS

Phase 1/2 Terminated

1 enrolled 4 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT01483690 2020-10-27

A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

Phase 1/2 Terminated

23 enrolled 13 charts

LymphoidOther hematologic neoplasm

Leukemia, Recurrence, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT01498445 2020-10-22

An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357)

Phase 1/2 Terminated

32 enrolled 16 charts

MyeloidOther hematologic neoplasm

Blast Crisis, Leukemia, Leukemia, Myelogenous, Chronic, BCR-ABL Positive

NCT02010645 2020-01-02

Eltrombopag With Decitabine in Advanced Myelodysplastic Syndrome (MDS)

Phase 2 Terminated

6 enrolled 8 charts

Other hematologic neoplasm

Leukemia, Leukemia, Myelomonocytic, Chronic

NCT02954653 2019-11-21

A Study Of PF-06747143, As Single Agent Or In Combination With Standard Chemotherapy In Adult Patients With Acute Myeloid Leukemia

Phase 1 Terminated

8 enrolled 13 charts

Other hematologic neoplasm

Recurrence, Leukemia, Myeloid, Acute

NCT02343939 2019-11-15

ENTO in AML

Phase 1/2 Terminated

148 enrolled 26 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02785900 2018-12-12

CASCADE

Phase 3 Terminated

240 enrolled 20 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02469415 2018-10-16

Pacritinib for Patients With Lower-Risk Myelodysplastic Syndromes (MDS)

Phase 2 Terminated

3 enrolled 6 charts

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes

NCT01846624 2018-09-27

Decitabine and Midostaurin in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Phase 2 Terminated

13 enrolled 12 charts

Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Myeloid, Acute

NCT02532010 2018-06-15

Pacritinib

Phase 2 Terminated

13 enrolled 10 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02332889 2018-05-04

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

Phase 1/2 Terminated

1 enrolled 6 charts

Glioma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT00882206 2017-12-28

Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

Phase 2 Terminated

15 enrolled 8 charts

LymphoidOther hematologic neoplasm

Leukemia, Lymphoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00925132 2017-07-02

Treatment of Resistant Metastatic Melanoma Using Decitabine, Temozolomide and Panobinostat

Phase 1/2 Terminated

39 enrolled 8 charts

Melanoma, Neoplasm Metastasis

NCT01607645 2017-03-31

Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS

Phase 2 Terminated

7 enrolled 17 charts

Classical hematologyOther hematologic neoplasm

Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT02029417 2016-05-09

Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

Phase 2 Terminated

2 enrolled 6 charts

Other hematologic neoplasm

Congenital Abnormalities, Leukemia, Erythroblastic, Acute, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute

NCT00630994 2015-12-30

Low-Dose Decitabine in Treating Patients With Symptomatic Myelofibrosis

Phase 2 Terminated

4 enrolled 11 charts

Myeloproliferative Disorders, Polycythemia Vera, Thrombocythemia, Essential, Primary Myelofibrosis

NCT01194908 2015-01-26

Re-expression of ER in Triple Negative Breast Cancers

Phase 1/2 Terminated

5 enrolled 5 charts

Breast Neoplasms

NCT00113321 2012-08-07

Low-Dose Decitabine in Myelodysplastic Syndrome Post Azacytidine Failure

Phase 2 Terminated

16 enrolled 6 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT00561912 2011-12-26

Low Dose Decitabine + Interferon Alfa-2b in Advanced Renal Cell Carcinoma

Phase 2 Terminated

2 enrolled 3 charts

Carcinoma, Renal Cell