Clinical Trials Browser

Interventional × Has results × Folic Acid × Clear all

NCT04024254 2026-03-04

A Study of Serum Folate Levels in Patients Treated With Olaparib

Phase 4 Completed

10 enrolled 14 charts

BreastGynecologic

Breast Neoplasms, Folic Acid Deficiency, Ovarian Neoplasms

NCT03564678 2025-09-05

Levocarnitine and Vitamin B Complex in Treating PEG-Asparaginase or Inotuzumab Ozogamicin-Induced Hyperbilirubinemia in Patients With Acute Lymphoblastic Leukemia

Phase 2 Terminated

10 enrolled 5 charts

LymphoidOther hematologic neoplasm

Hyperbilirubinemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04786964 2025-04-02

CONTERNO

Phase 3 Terminated

25 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT02578680 2024-09-20

MK-3475-189

Phase 3 Completed

616 enrolled 19 charts 1 FDA

Carcinoma, Non-Small-Cell Lung

NCT03950674 2024-06-10

MK-3475-189

Phase 3 Completed

40 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT00402883 2021-11-09

Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer

Phase 2 Terminated

5 enrolled 6 charts

Lung Neoplasms

NCT00998946 2021-11-05

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Phase 2 Completed

29 enrolled 8 charts

Recurrence, Lymphoma, B-Cell

NCT00606502 2021-03-05

Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment

Phase 2 Completed

201 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Smoking

NCT00481871 2020-01-07

Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies

Phase 1/2 Completed

119 enrolled 13 charts

LymphoidOther hematologic neoplasm

Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Recurrence, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Extranodal NK-T-Cell

NCT01118624 2020-01-07

Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer

Phase 2 Completed

22 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00722553 2019-12-17

Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder

Phase 2 Completed

30 enrolled 12 charts

Urinary Bladder Neoplasms, Carcinoma, Carcinoma, Transitional Cell, Neoplasm Metastasis, Recurrence

NCT00923273 2019-11-26

Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer

Phase 1/2 Terminated

42 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03349333 2019-10-01

A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCL

Phase 3 Completed

85 enrolled 26 charts

Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral

NCT01165021 2019-09-25

A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung Cancer

Phase 2 Completed

19 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT01188876 2018-01-19

Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer

Phase 1/2 Completed

50 enrolled 15 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Recurrence

NCT00932113 2017-08-31

MOA

Phase 4 Completed

33 enrolled 11 charts

Psoriasis

NCT00227019 2017-03-06

Phase 2 Trial of Bevacizumab in Combination With Pemetrexed

Phase 2 Completed

16 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT00806819 2017-02-02

Lume Lung 2 : BIBF 1120 Plus Pemetrexed Compared to Placebo Plus Pemetrexed in 2nd Line Nonsquamous NSCLC

Phase 3 Completed

718 enrolled 21 charts

Carcinoma, Non-Small-Cell Lung

NCT00216099 2016-07-29

Pemetrexed as Second-Line Therapy in Treating Patients With Hormone Refractory Prostate Cancer

Phase 2 Completed

49 enrolled 15 charts

Prostatic Neoplasms

NCT01194453 2016-06-16

AP/GP

Phase 2 Completed

288 enrolled 8 charts

Carcinoma, Non-Small-Cell Lung

NCT01183065 2015-11-20

Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

Phase 2 Completed

13 enrolled 6 charts

Head and Neck Neoplasms

NCT01283971 2014-02-10

A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor

Phase 4 Terminated

96 enrolled 27 charts

Arthritis, Rheumatoid

NCT01057589 2013-09-18

A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

Phase 2 Completed

66 enrolled 11 charts

Head and Neck Neoplasms, Laryngeal Diseases, Thyroid Diseases

NCT00609518 2010-12-28

A Study for Patients With Non-Squamous Non-Small Cell Lung Cancer

Phase 2 Completed

111 enrolled 17 charts

Carcinoma, Non-Small-Cell Lung