Announcements Trials
Browse Landscape

Phase

Phase 1 5

Status

Completed 3Terminated 2

Sponsor Class

NIH 22INDUSTRY 5OTHER 4

Study Type

Interventional 5

Sponsor

Cancer Type

Tumor-Agnostic 2Other solid neoplasm 1Gynecologic 1Gastrointestinal 1Breast 1

Conditions

Neoplasms 3Ovarian Neoplasms 1Locally Advanced or Metastatic Solid Tumors 1Fallopian Tube Neoplasms 1Colorectal Neoplasms 1Breast Neoplasms 1

Interventions

Paclitaxel 337pembrolizumab 332Carboplatin 330Cisplatin 277Gemcitabine 264Docetaxel 251Bevacizumab 239Nivolumab 230Pemetrexed 211Rituximab 183Dexamethasone 183Cyclophosphamide 169Capecitabine 169Trastuzumab 149Fluorouracil 147Ipilimumab 121atezolizumab 118Prednisone 117Erlotinib Hydrochloride 116Oxaliplatin 109Cetuximab 104Sunitinib 101Leucovorin 97Doxorubicin 97Lenalidomide 93Irinotecan 89130-nm albumin-bound paclitaxel 84durvalumab 77Bortezomib 77Azacitidine 73

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
INDUSTRY × Has results × MK 2206 × Clear all
NCT00963547 2024-06-04

MK-2206-015

Merck Sharp & Dohme LLC

Phase 1 Terminated
33 enrolled 13 charts
Breast

Breast Neoplasms

NCT00848718 2019-11-12

MK-2206-003

Merck Sharp & Dohme LLC

Phase 1 Completed
77 enrolled 24 charts
Tumor-Agnostic

Neoplasms

NCT00670488 2019-04-01

MK-2206-002

Merck Sharp & Dohme LLC

Phase 1 Completed
104 enrolled 28 charts
Tumor-Agnostic

Neoplasms

NCT01243762 2018-08-16

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Merck Sharp & Dohme LLC

Phase 1 Terminated
47 enrolled 12 charts
GastrointestinalGynecologic

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT01021748 2018-08-07

A Combination Therapy Study of MK-2206 and AZD6244 in Participants With Advanced Solid Tumors (MK-2206-010)

Merck Sharp & Dohme LLC

Phase 1 Completed
63 enrolled 17 charts
Other solid neoplasm

Locally Advanced or Metastatic Solid Tumors

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