Clinical Trials Browser

NCT02113878 2024-11-05

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Phase 1 Completed

23 enrolled 22 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Nasopharyngeal Neoplasms

NCT02220855 2022-04-11

A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas

Phase 2 Completed

14 enrolled 14 charts

Thoracic

Thymoma

NCT01816984 2021-10-05

PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer

Phase 1/2 Completed

12 enrolled 11 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck, Salivary Gland Neoplasms, Tongue Neoplasms

NCT01695473 2021-01-13

Neoadjuvant BKM120 in High-risk Prostate Cancer

Phase 2 Terminated

11 enrolled 8 charts

Genitourinary

Prostatic Neoplasms

NCT01629615 2020-10-28

A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer

Phase 2 Completed

50 enrolled 10 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT01349660 2020-06-17

Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme

Phase 1/2 Completed

88 enrolled 13 charts

CNS

Glioblastoma

NCT02128724 2019-08-01

BKM120

Phase 1 Completed

21 enrolled 23 charts

Thoracic

Hypoxia, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT01339052 2019-03-19

Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma

Phase 2 Completed

65 enrolled 30 charts

CNS

Brain Neoplasms, Glioblastoma

NCT01487265 2019-03-06

Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to Erlotinib

Phase 2 Completed

37 enrolled 10 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02303041 2019-01-29

Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma

Phase 2 Terminated

10 enrolled 11 charts

Dermatologic

Basal Cell Nevus Syndrome, Carcinoma, Basal Cell, Skin Neoplasms

NCT01790932 2019-01-23

BKM120 For Triple Negative Breast Cancer

Phase 2 Completed

50 enrolled 8 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT02301364 2017-10-19

Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Phase 2 Completed

4 enrolled 11 charts

Lymphoid

Lymphoma, Recurrence

NCT01385293 2017-05-19

BKM120 in Metastatic Castration-resistant Prostate Cancer

Phase 2 Terminated

30 enrolled 11 charts

Genitourinary

Neoplasm Metastasis, Prostatic Neoplasms