Announcements Trials
Browse Landscape

Phase

Phase 1/2 3Phase 2 2Phase 1 1

Status

Terminated 4Completed 2

Sponsor Class

OTHER 6

Study Type

Interventional 6

Sponsor

Cancer Type

CNS 6Sarcoma 1Breast 1

Conditions

Neuroblastoma 3Brain Neoplasms 3Medulloblastoma 2Glioblastoma 2Recurrence 1Gliosarcoma 1Central Nervous System Neoplasms 1Breast Neoplasms 1

Interventions

Cyclophosphamide 908Carboplatin 785Paclitaxel 739pembrolizumab 738Cisplatin 707Bevacizumab 705Gemcitabine 619Docetaxel 578Rituximab 548Radiotherapy 539Dexamethasone 510Nivolumab 485Doxorubicin 444Fluorouracil 392Capecitabine 376Etoposide 357Pemetrexed 334Cytarabine 334Oxaliplatin 333Lenalidomide 327Prednisone 326fludarabine phosphate 315Erlotinib Hydrochloride 314Trastuzumab 300Leucovorin 299fludarabine 296Vincristine 287Filgrastim 284Bortezomib 284Cetuximab 274

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Interventional × Has results × TPI-287 × Clear all
NCT00867568 2024-08-06

TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma

Milton S. Hershey Medical Center

Phase 1 Completed
18 enrolled 12 charts
CNS

Medulloblastoma, Neuroblastoma, Recurrence

NCT01483820 2024-08-06

Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma

Milton S. Hershey Medical Center

Phase 1/2 Terminated
8 enrolled 9 charts
CNS

Medulloblastoma, Neuroblastoma

NCT01505608 2024-08-06

Randomized Efficacy Study of TPI 287 to Treat Primary Refractory or Early Relapsed Neuroblastoma

Milton S. Hershey Medical Center

Phase 1/2 Terminated
14 enrolled 11 charts
CNS

Neuroblastoma

NCT01582152 2019-06-05

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

M.D. Anderson Cancer Center

Phase 1/2 Terminated
12 enrolled 7 charts
CNSSarcoma

Brain Neoplasms, Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT01332630 2018-09-20

TPI 287 in Breast Cancer Metastatic to the Brain

M.D. Anderson Cancer Center

Phase 2 Completed
24 enrolled 8 charts
BreastCNS

Brain Neoplasms, Breast Neoplasms

NCT01113463 2016-10-31

TPI 287 in Patients With Recurrent Glioblastoma Multiforme

M.D. Anderson Cancer Center

Phase 2 Terminated
17 enrolled 3 charts
CNS

Brain Neoplasms, Glioblastoma

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