Clinical Trials Browser

Phase 3 × Has results × Zoledronic Acid × Clear all

NCT00365105 2024-09-20

Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer

Phase 3 Completed

261 enrolled 12 charts

BreastGenitourinaryThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis, Pain, Prostatic Neoplasms

NCT00295646 2024-03-15

Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

Phase 3 Completed

1,803 enrolled 20 charts

Breast Neoplasms

NCT00556374 2023-07-27

Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

Phase 3 Completed

3,420 enrolled 19 charts

Breast Neoplasms

NCT00321464 2022-11-08

A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

Phase 3 Completed

2,049 enrolled 16 charts

Breast Neoplasms, Fractures, Bone

NCT01345019 2022-11-08

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Phase 3 Completed

1,718 enrolled 22 charts

Other hematologic neoplasmPlasma cellSarcoma

Blood Protein Disorders, Bone Diseases, Bone Marrow Diseases, Bone Neoplasms, Hematologic Diseases, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Neoplastic Processes, Paraproteinemias, Spinal Cord Compression, Hematologic Neoplasms, Fractures, Bone, Neoplasms, Plasma Cell

NCT00330759 2022-11-07

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.

Phase 3 Completed

1,779 enrolled 14 charts

LymphoidPlasma cell

Lymphoma, Multiple Myeloma, Spinal Cord Compression

NCT00127205 2021-07-02

S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

Phase 3 Completed

6,097 enrolled 20 charts

Breast Neoplasms

NCT00058188 2020-12-08

Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

Phase 3 Terminated

Osteoporosis, Prostatic Neoplasms

NCT00079001 2020-05-12

Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

Phase 3 Completed

645 enrolled 13 charts

Neoplasm Metastasis, Prostatic Neoplasms

NCT00869206 2018-11-07

Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

Phase 3 Completed

1,822 enrolled 19 charts

BreastGenitourinaryPlasma cell

Breast Neoplasms, Multiple Myeloma, Pain, Prostatic Neoplasms

NCT00321620 2018-08-29

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

Phase 3 Completed

1,904 enrolled 15 charts

Fractures, Bone

NCT00329797 2017-11-29

Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

Phase 3 Completed

109 enrolled 8 charts

Osteoporosis, Prostatic Neoplasms

NCT01920568 2017-01-16

A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors

Phase 3 Completed

487 enrolled 13 charts

Fractures, Bone

NCT02739594 2016-07-22

COMPARE

Phase 3 Terminated

89 enrolled 17 charts

Multiple Myeloma

NCT00375505 2015-09-07

The Safety and Efficacy of Zoledronic Acid in the Prevention of Cancer Therapy Induced Bone Loss

Phase 3 Completed

70 enrolled 25 charts

Breast Neoplasms

NCT00172042 2015-05-04

A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

Phase 3 Completed

437 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT00320710 2014-08-22

Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer

Phase 3 Completed

416 enrolled 10 charts

Breast Neoplasms

NCT00242567 2014-05-07

Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer

Phase 3 Completed

522 enrolled 8 charts

Prostatic Neoplasms

NCT00712985 2014-04-24

CTIBL

Phase 3 Completed

18 enrolled 5 charts

Breast Neoplasms

NCT00215943 2014-04-17

Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)

Phase 3 Terminated

90 enrolled 10 charts

Other hematologic neoplasmPlasma cell

Multiple Myeloma, Hematologic Neoplasms

NCT00050011 2014-03-21

Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

Phase 3 Completed

602 enrolled 13 charts

Bone Diseases, Metabolic, Breast Neoplasms, Osteoporosis

NCT00352846 2013-07-02

Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss

Phase 3 Completed

135 enrolled 4 charts

Bone Diseases, Metabolic, Lymphoma, Lymphoma, Non-Hodgkin

NCT00432458 2012-07-04

Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma

Phase 3 Completed

68 enrolled 16 charts

Multiple Myeloma, Neoplasms, Plasma Cell

NCT00171340 2012-04-16

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

Phase 3 Completed

1,065 enrolled 10 charts

Bone Diseases, Metabolic, Breast Neoplasms

NCT00171314 2012-04-11

The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

Phase 3 Completed

527 enrolled 11 charts

Breast Neoplasms

NCT00171925 2012-04-11

Therapy With Zoledronic Acid in Patients With Multiple Myeloma Stage I

Phase 3 Terminated

143 enrolled 10 charts

Multiple Myeloma, Disease Progression

NCT00375427 2012-04-11

Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

Phase 3 Completed

430 enrolled 12 charts

Breast Neoplasms

NCT00332709 2011-11-16

Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

Phase 3 Completed

83 enrolled 14 charts

Breast Neoplasms, Osteoporosis