Announcements Trials
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Phase

Phase 2 3Phase 3 1Phase 1/2 1

Status

Completed 4Terminated 1

Sponsor Class

INDUSTRY 5

Study Type

Interventional 5

Sponsor

Cancer Type

Head & Neck 3Gastrointestinal 1

Conditions

Stomatitis 3Head and Neck Neoplasms 2Squamous Cell Carcinoma of Head and Neck 1Pancreatic Neoplasms 1Oral Ulcer 1Esophagitis 1Carcinoma, Squamous Cell 1

Interventions

Cyclophosphamide 909Carboplatin 786pembrolizumab 743Paclitaxel 742Cisplatin 708Bevacizumab 706Gemcitabine 619Docetaxel 579Rituximab 548Radiotherapy 541Dexamethasone 511Nivolumab 488Doxorubicin 444Fluorouracil 392Capecitabine 376Etoposide 358Pemetrexed 336Cytarabine 335Oxaliplatin 333Lenalidomide 328Prednisone 326fludarabine phosphate 316Erlotinib Hydrochloride 314Trastuzumab 300Leucovorin 299fludarabine 296Vincristine 287Filgrastim 284Bortezomib 284Cetuximab 276

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × Has results × avasopasem manganese × Clear all
NCT03340974 2023-12-15

Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer

Galera Therapeutics, Inc.

Phase 1/2 Completed
42 enrolled 13 charts
Gastrointestinal

Pancreatic Neoplasms

NCT03689712 2023-10-24

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

Galera Therapeutics, Inc.

Phase 3 Completed
455 enrolled 11 charts
Head & Neck

Carcinoma, Squamous Cell, Head and Neck Neoplasms, Stomatitis, Oral Ulcer

NCT04225026 2023-03-23

Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung Cancer

Galera Therapeutics, Inc.

Phase 2 Terminated
39 enrolled 12 charts

Esophagitis

NCT04529850 2022-08-16

Ph 2 Open Label Study of GC4419 to Reduce SOM Associated With Chemoradiotherapy for Head and Neck Cancer

Galera Therapeutics, Inc.

Phase 2 Completed
38 enrolled 10 charts
Head & Neck

Head and Neck Neoplasms, Stomatitis

NCT02508389 2021-09-20

A Study of the Effects of GC4419 on Radiation Induced Oral Mucositis in Patients With Head/Neck Cancer

Galera Therapeutics, Inc.

Phase 2 Completed
223 enrolled 17 charts
Head & Neck

Squamous Cell Carcinoma of Head and Neck, Stomatitis

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