Announcements Trials
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Phase

Phase 1/2 8Phase 2 7Phase 1 5Phase 3 1

Status

Completed 3Terminated 2

Sponsor Class

INDUSTRY 4NIH 1

Study Type

Interventional 5

Sponsor

Cancer Type

Tumor-Agnostic 2Other solid neoplasm 1Gynecologic 1Breast 1

Conditions

Neoplasms 2Uterine Cervical Neoplasms 1Triple Negative Breast Neoplasms 1Metastatic Solid Tumors 1Camurati-Engelmann Syndrome 1Breast Neoplasms 1

Interventions

pembrolizumab 109Paclitaxel 65Cyclophosphamide 65Cisplatin 60Carboplatin 56Gemcitabine 48Radiotherapy 45Nivolumab 44fludarabine 38Docetaxel 38Pemetrexed 33Dexamethasone 32Capecitabine 32Lenalidomide 26fludarabine phosphate 25Rituximab 25Radiation 25Ipilimumab 25Doxorubicin 25Irinotecan 24Bevacizumab 24Azacitidine 24Vorinostat 23Vincristine 22Cytarabine 22Temozolomide 20Etoposide 20Oxaliplatin 19Fluorouracil 19atezolizumab 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Phase 1 × Has results × bintrafusp alfa protein, human × Clear all
NCT04457778 2026-05-04

First in Human Study of M6223

EMD Serono

Phase 1 Completed
58 enrolled 38 charts
Other solid neoplasm

Metastatic Solid Tumors

NCT02723955 2024-12-27

Dose Escalation and Expansion Study of GSK3359609 in Participants With Selected Advanced Solid Tumors (INDUCE-1)

GlaxoSmithKline

Phase 1 Completed
829 enrolled 100 charts
Tumor-Agnostic

Neoplasms

NCT04349280 2024-04-18

A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer

GlaxoSmithKline

Phase 1 Terminated
25 enrolled 10 charts
Tumor-Agnostic

Neoplasms

NCT04551950 2024-03-08

Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)

EMD Serono

Phase 1 Completed
25 enrolled 14 charts
Gynecologic

Uterine Cervical Neoplasms, Camurati-Engelmann Syndrome

NCT04296942 2022-01-11

BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)

National Institutes of Health Clinical Center (CC)

Phase 1 Terminated
1 enrolled 10 charts
Breast

Breast Neoplasms, Triple Negative Breast Neoplasms

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