Announcements Trials
Browse Landscape

Phase

Phase 2 6Phase 3 2Phase 1/2 1Phase 1 1

Status

Terminated 3Completed 3

Sponsor Class

INDUSTRY 4OTHER 1NIH 1

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 6CNS 1

Conditions

Lung Neoplasms 2Carcinoma, Non-Small-Cell Lung 2ALK-positive Advanced NSCLC 2Brain Neoplasms 1

Interventions

Cyclophosphamide 517Bevacizumab 488Carboplatin 424pembrolizumab 388Paclitaxel 385Gemcitabine 372Cisplatin 366Docetaxel 323Rituximab 316Radiotherapy 296Nivolumab 247Doxorubicin 243Dexamethasone 240Fluorouracil 225Capecitabine 214Oxaliplatin 211Erlotinib Hydrochloride 206fludarabine phosphate 201Etoposide 188Cetuximab 186Lenalidomide 177Pemetrexed 176Bortezomib 174Trastuzumab 173Filgrastim 171fludarabine 166Prednisone 166Leucovorin 166Cytarabine 166Irinotecan 161

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × Has results × brigatinib × Clear all
NCT03737994 2026-04-23

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

National Cancer Institute (NCI)

Phase 2 Terminated
10 enrolled 17 charts
Thoracic

Lung Neoplasms

NCT03535740 2025-07-31

ALTA-2

Takeda

Phase 2 Completed
103 enrolled 23 charts
Thoracic

ALK-positive Advanced NSCLC

NCT03410108 2024-05-08

Phase 2 Study of Brigatinib in Japanese Participants With Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small Cell Lung Cancer (NSCLC)

Takeda

Phase 2 Completed
104 enrolled 22 charts
Thoracic

ALK-positive Advanced NSCLC

NCT02706626 2023-01-26

Trial of Brigatinib After Treatment With Next-Generation ALK Inhibitors

Criterium, Inc.

Phase 2 Terminated
32 enrolled 9 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT04634110 2022-10-24

Brigatinib Before Brain Irradiation Trial (B3i Trial)

University of Colorado, Denver

Phase 2 Terminated
1 enrolled 6 charts
CNSThoracic

Brain Neoplasms, Lung Neoplasms

NCT02094573 2021-03-15

A Study to Evaluate the Efficacy of Brigatinib (AP26113) in Participants With Anaplastic Lymphoma Kinase (ALK)-Positive, Non-small Cell Lung Cancer (NSCLC) Previously Treated With Crizotinib

Takeda

Phase 2 Completed
222 enrolled 23 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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