Clinical Trials

61 enrolled 9 charts

Endocrine

Carcinoid Tumor, Adenoma, Islet Cell, Neoplasm Metastasis

NCT01755195 2024-01-03

Cabozantinib for Adults With Advanced Soft Tissue Sarcoma

55 enrolled 16 charts

Sarcoma

NCT01709435 2023-12-22

Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid Tumors

CNSDermatologicHead & Neck

41 enrolled 20 charts

Melanoma, Thyroid Neoplasms, Central Nervous System Neoplasms, Carcinoma, Medullary

NCT02795156 2023-12-05

Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations

100 enrolled 14 charts

GenitourinaryThoracic

Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell

NCT03468985 2023-10-17

Nivolumab, Cabozantinib S-Malate, and Ipilimumab in Treating Patients With Recurrent Stage IV Non-small Cell Lung Cancer

3 enrolled 10 charts

Metastatic Lung Non-Squamous Non-Small Cell Carcinoma

NCT02101736 2023-05-24

NF105-CABO

45 enrolled 10 charts

CNS

Neurofibromatoses, Neurofibroma, Plexiform

NCT03428217 2023-03-20

CANTATA

444 enrolled 15 charts

Carcinoma, Renal Cell, Kidney Neoplasms

NCT01822522 2023-01-10

Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency Virus

36 enrolled 18 charts

Neoplasm Metastasis, HIV Infections

NCT01688999 2022-10-18

Cabozantinib for Advanced Urothelial Cancer

69 enrolled 14 charts

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Kidney Neoplasms, Urethral Neoplasms

NCT01835145 2022-08-04

Cabozantinib-S-Malate Compared With Temozolomide or Dacarbazine in Treating Patients With Metastatic Melanoma of the Eye That Cannot Be Removed by Surgery

47 enrolled 12 charts

Dermatologic

Uveal Melanoma

NCT03542877 2022-07-15

Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer

44 enrolled 19 charts

Neoplasms, Colorectal Neoplasms

NCT01630590 2022-03-25

Cabozantinib and Androgen Ablation in Patients With Androgen-Dependent Metastatic Prostate Cancer

62 enrolled 15 charts

Prostatic Neoplasms

NCT03316586 2021-12-28

A Phase II Study of Nivolumab in Combination With Cabozantinib for Metastatic Triple-negative Breast Cancer

18 enrolled 16 charts

Breast

Breast Neoplasms

NCT01812668 2021-08-05

Cabozantinib-S-Malate in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer

Phase NA Completed

20 enrolled 12 charts

Prostatic Neoplasms

NCT02260531 2021-05-20

Cabozantinib +/- Trastuzumab In Breast Cancer Patients w/ Brain Metastases

707 enrolled 20 charts 1 FDA

36 enrolled 19 charts

BreastCNS

Brain Neoplasms, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT01908426 2021-05-06

CELESTIAL

Phase 3 Completed

Carcinoma, Hepatocellular, Liver Neoplasms

NCT01865747 2021-04-27

METEOR

Phase 3 Completed

658 enrolled 15 charts

Carcinoma, Renal Cell

NCT01835158 2021-02-11

Cabozantinib-s-malate or Sunitinib Malate in Treating Patients With Previously Untreated Locally Advanced or Metastatic Kidney Cancer

157 enrolled 10 charts 1 FDA

Carcinoma, Renal Cell

NCT01588821 2020-09-29

Cabozantinib in Advanced Solid Malignancies

37 enrolled 10 charts

GenitourinaryThoracic

Lung Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms, Recurrence

NCT01599793 2020-03-26

Magnetic Resonance Imaging in Measuring the Effect of Cabozantinib in Patients With Castrate Resistant Prostate Cancer

19 enrolled 11 charts

Prostatic Neoplasms

NCT01716715 2020-03-10

Cabozantinib or Paclitaxel in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

111 enrolled 13 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT02315430 2020-03-10

Cabozantinib-S-Malate in Treating Patients With Recurrent or Progressive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

13 enrolled 11 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT01683994 2019-11-08

Cabozantinib Plus Docetaxel and Prednisone for Advanced Prostate Cancer

Phase 1/2 Completed

49 enrolled 18 charts

Prostatic Neoplasms

NCT01866410 2019-05-16

Cabozantinib-S-Malate and Erlotinib Hydrochloride in Treating Patients With Previously Treated Metastatic Non-Small Cell Lung Cancer

37 enrolled 13 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01663272 2018-09-19

A Trial of Cabozantinib (XL184) and Gemcitabine in Advanced Pancreatic Cancer

12 enrolled 6 charts

Neoplasms, Pancreatic Neoplasms

NCT01605227 2018-03-14

COMET-1

Phase 3 Completed

1,028 enrolled 18 charts

Pain, Prostatic Neoplasms

NCT01834651 2017-09-27

A Phase II Study of Cabozantinib (XL184) Therapy in Castrate Resistant Prostate Cancer (CRPC) With Visceral Metastases

17 enrolled 11 charts

Prostatic Neoplasms

NCT01866293 2017-08-30

Cabozantinib (XL184) in Patients With Relapsed or Refractory Myeloma

Phase 1/2 Completed

11 enrolled 12 charts

Plasma cell

Multiple Myeloma, Recurrence

NCT01954745 2017-02-03

Cabozantinib (XL-184) Monotherapy for Advanced Cholangiocarcinoma

19 enrolled 8 charts

Bile Duct Neoplasms, Cholangiocarcinoma

NCT01738438 2016-12-06

Cabozantinib for Metastatic Triple Negative BrCa

35 enrolled 7 charts

Breast

Breast Neoplasms, Neoplasm Metastasis

NCT01347788 2016-11-28

Cabozantinib (XL184) in Men With Castrate-Resistant Prostate Cancer

34 enrolled 6 charts