Announcements Trials
Browse Landscape

Phase

Phase 1 6Phase 2 5Phase 1/2 2

Status

Completed 5Terminated 1

Sponsor Class

INDUSTRY 6

Study Type

Interventional 6

Sponsor

Cancer Type

Gastrointestinal 2Tumor-Agnostic 1Plasma cell 1Other solid neoplasm 1Gynecologic 1Breast 1

Conditions

Neoplasms 2Colorectal Neoplasms 2Ovarian Neoplasms 1Multiple Myeloma 1Fallopian Tube Neoplasms 1Breast Neoplasms 1Advanced Solid Tumors 1

Interventions

pembrolizumab 109Paclitaxel 65Cyclophosphamide 65Cisplatin 60Carboplatin 56Gemcitabine 48Radiotherapy 45Nivolumab 44fludarabine 38Docetaxel 38Pemetrexed 33Dexamethasone 32Capecitabine 32Lenalidomide 26fludarabine phosphate 25Rituximab 25Radiation 25Ipilimumab 25Doxorubicin 25Irinotecan 24Bevacizumab 24Azacitidine 24Vorinostat 23Vincristine 22Cytarabine 22Temozolomide 20Etoposide 20Oxaliplatin 19Fluorouracil 19atezolizumab 17

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 1 × Has results × dalotuzumab × Clear all
NCT00635778 2018-10-09

MK-0646-002

Merck Sharp & Dohme LLC

Phase 1 Completed
50 enrolled 32 charts
Other solid neoplasm

Advanced Solid Tumors

NCT01243762 2018-08-16

A Study of Dalotuzumab + MK-2206, Dalotuzumab + MK-0752, and Dalotuzumab + Ridaforolimus Combination Therapies in Participants With Advanced Cancer (MK-0646-027)

Merck Sharp & Dohme LLC

Phase 1 Terminated
47 enrolled 12 charts
GastrointestinalGynecologic

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms, Colorectal Neoplasms

NCT00759785 2018-08-15

MK-0646-013

Merck Sharp & Dohme LLC

Phase 1 Completed
48 enrolled 10 charts
Breast

Breast Neoplasms

NCT00925015 2018-08-15

Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016)

Merck Sharp & Dohme LLC

Phase 1 Completed
20 enrolled 30 charts
Gastrointestinal

Colorectal Neoplasms

NCT00694356 2018-08-08

Study of Dalotuzumab (MK-0646) in Adults With Solid Tumors (MK-0646-009)

Merck Sharp & Dohme LLC

Phase 1 Completed
15 enrolled 13 charts
Tumor-Agnostic

Neoplasms

NCT00701103 2018-08-08

Dose Escalation Trial of Dalotuzumab (MK-0646) in Advanced Solid Tumors and Multiple Myeloma (MK-0646-001)

Merck Sharp & Dohme LLC

Phase 1 Completed
80 enrolled 23 charts
Plasma cell

Multiple Myeloma

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