NCT05282459 2026-04-17Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 MutationStanford UniversityPhase 1/2 Completed17 enrolled 12 charts
NCT02677922 2026-02-19A Study to Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction ChemotherapyCelgenePhase 1/2 Active not recruiting130 enrolled 38 charts
NCT04281498 2025-02-04Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 MutationIcahn School of Medicine at Mount SinaiPhase 2 Completed6 enrolled 11 charts
NCT01915498 2024-10-22Phase 1/2 Study of Enasidenib (AG-221) in Adults With Advanced Hematologic Malignancies With an Isocitrate Dehydrogenase Isoform 2 (IDH2) MutationCelgenePhase 1/2 Completed345 enrolled 120 charts 2 FDA
NCT02273739 2021-02-23Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 MutationCelgenePhase 1/2 Completed21 enrolled 33 charts