Announcements Trials
Browse Landscape

Phase

Phase 2 6Phase 1/2 5Phase 1 5Phase 3 4

Status

Completed 5Active not recruiting 1

Sponsor Class

INDUSTRY 5NIH 1

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 2Tumor-Agnostic 1Plasma cell 1Lymphoid 1Gastrointestinal 1

Conditions

Breast Neoplasms 2Stomach Neoplasms 1Neoplasms, Unknown Primary 1Multiple Myeloma 1Lymphoma 1Advanced Unresectable or Metastatic Solid Malignancy 1

Interventions

Cyclophosphamide 517Bevacizumab 488Carboplatin 424pembrolizumab 388Paclitaxel 385Gemcitabine 372Cisplatin 366Docetaxel 323Rituximab 316Radiotherapy 296Nivolumab 247Doxorubicin 243Dexamethasone 240Fluorouracil 225Capecitabine 214Oxaliplatin 211Erlotinib Hydrochloride 206fludarabine phosphate 201Etoposide 188Cetuximab 186Lenalidomide 177Pemetrexed 176Bortezomib 174Trastuzumab 173Filgrastim 171fludarabine 166Prednisone 166Leucovorin 166Cytarabine 166Irinotecan 161

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × Has results × ipatasertib × Clear all
NCT06400251 2026-06-01

Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes (MATCH - Subprotocol Z1K)

National Cancer Institute (NCI)

Phase 2 Active not recruiting
35 enrolled 10 charts
LymphoidPlasma cell

Lymphoma, Multiple Myeloma

NCT03498521 2025-11-19

CUPISCO

Hoffmann-La Roche

Phase 2 Completed
529 enrolled 16 charts
Tumor-Agnostic

Neoplasms, Unknown Primary

NCT04632992 2025-01-08

MyTACTIC

Genentech, Inc.

Phase 2 Completed
252 enrolled 27 charts

Advanced Unresectable or Metastatic Solid Malignancy

NCT01896531 2022-03-02

A Study of Ipatasertib (GDC-0068) in Combination With Fluoropyrimidine Plus Oxaliplatin in Participants With Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer

Genentech, Inc.

Phase 2 Completed
153 enrolled 16 charts
Gastrointestinal

Stomach Neoplasms

NCT02162719 2021-03-10

LOTUS

Genentech, Inc.

Phase 2 Completed
124 enrolled 26 charts
Breast

Breast Neoplasms

NCT02301988 2018-10-17

A Study of Ipatasertib (GDC-0068) in Combination With Paclitaxel as Neoadjuvant Treatment for Participants With Early Stage Triple Negative Breast Cancer

Genentech, Inc.

Phase 2 Completed
151 enrolled 22 charts
Breast

Breast Neoplasms

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