Clinical Trials Browser

Interventional × Has results × nirogacestat × Clear all

NCT04126200 2026-05-06

DREAMM 5

Phase 1/2 Active not recruiting

208 enrolled 5 charts

Multiple Myeloma

NCT07084896 2026-05-06

Sub-study of Belantamab Mafodotin (GSK2857916) in Combination With Nirogacestat in Participants With RRMM

Phase 1/2 Active not recruiting

106 enrolled 32 charts

Multiple Myeloma

NCT05090566 2026-04-24

MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma

Phase 2 Terminated

46 enrolled 15 charts

Multiple Myeloma

NCT03785964 2025-01-31

DeFi

Phase 3 Completed

142 enrolled 21 charts 1 FDA

Desmoid Tumors

NCT01981551 2024-02-06

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis

Phase 2 Completed

17 enrolled 14 charts

Desmoid Tumors

NCT00878189 2019-11-12

A Trial In Patients With Advanced Cancer And Leukemia

Phase 1 Completed

72 enrolled 49 charts

Other hematologic neoplasm

Leukemia, Neoplasms by Histologic Type

NCT01876251 2019-03-15

A Study Evaluating The PF-03084014 In Combination With Docetaxel In Patients With Advanced Breast Cancer

Phase 1 Terminated

30 enrolled 29 charts

Breast Cancer Metastatic

NCT02109445 2019-01-10

Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapies

Phase 2 Terminated

3 enrolled 15 charts

Gastrointestinal

Pancreatic Neoplasms

NCT02299635 2019-01-08

A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations

Phase 2 Terminated

19 enrolled 9 charts

Triple Negative Breast Neoplasms