Clinical Trials Browser

Phase 1 × Terminated × Has results × Clear all

NCT05839600 2026-05-22

A Study to Find a Suitable Dose of BI 1821736 and Test Whether it Helps People With Advanced Cancer

Phase 1 Terminated

10 enrolled 12 charts

Other solid neoplasm

Solid Tumors

NCT03144466 2026-05-20

PAPAYA

Phase 1 Terminated

1 enrolled 7 charts

Uterine Cervical Neoplasms

NCT05582850 2026-05-12

EPRAD

Phase 1 Terminated

29 enrolled 12 charts

Other solid neoplasm

Solid Tumor, Adult

NCT03334305 2026-04-23

ACTION

Phase 1 Terminated

18 enrolled 11 charts

Glioma

NCT05198349 2026-04-22

First in Human Study of M1069 in Advanced Solid Tumors

Phase 1 Terminated

15 enrolled 18 charts

Neoplasm Metastasis

NCT03646188 2026-04-16

Dose Escalation Trial to Evaluate Dose Limiting Toxicity/Maximum Tolerated Dose of Microneedle Arrays Containing Doxorubicin (D-MNA) in Basal Cell Carcinoma (BCC)

Phase 1 Terminated

13 enrolled 12 charts

Carcinoma, Basal Cell

NCT02819752 2026-04-09

PEACH

Phase 1 Terminated

3 enrolled 12 charts

Squamous Cell Carcinoma of Head and Neck, Carcinoma, Squamous Cell

NCT05765734 2026-04-02

TAS3351

Phase 1 Terminated

18 enrolled 22 charts

Carcinoma, Non-Small-Cell Lung

NCT04234113 2026-03-27

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Phase 1 Terminated

115 enrolled 43 charts

BreastDermatologicGastrointestinalGenitourinaryGynecologicHead & NeckOther solid neoplasmThoracic

Squamous Cell Carcinoma of Head and Neck, Anus Neoplasms, Biliary Tract Neoplasms, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Carcinoma, Renal Cell, Uterine Cervical Neoplasms, Carcinoma, Hepatocellular, Melanoma, Mesothelioma, Ovarian Neoplasms, Stomach Neoplasms, Thymus Neoplasms, Thyroid Neoplasms, Carcinoma, Merkel Cell, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms

NCT04762602 2026-03-27

A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations

Phase 1 Terminated

42 enrolled 26 charts

CNSGastrointestinal

Glioma, Cholangiocarcinoma

NCT05275439 2026-03-18

Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML

Phase 1 Terminated

106 enrolled 28 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03772925 2026-03-03

Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Phase 1 Terminated

18 enrolled 19 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03779113 2026-02-18

An Open-label, Dose Escalation Trial to Evaluate the Safety and Pharmacokinetics of HMPL-523 in Patients With Lymphoma

Phase 1 Terminated

69 enrolled 47 charts

LymphoidOther hematologic neoplasm

Hodgkin Disease, Lymphoma, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell

NCT04504331 2026-02-12

Study of Infigratinib in Combination With Tamoxifen in Hormone Receptor Positive, HER2 Negative, FGFR Altered Advanced Breast Cancer

Phase 1 Terminated

4 enrolled 11 charts

Breast Neoplasms

NCT03031730 2026-02-10

Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma

Phase 1 Terminated

35 enrolled 10 charts

Multiple Myeloma, Plasmacytoma

NCT03237572 2026-02-09

Breast-48

Phase 1 Terminated

13 enrolled 10 charts

Breast Neoplasms

NCT04081688 2026-02-05

Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC

Phase 1 Terminated

16 enrolled 9 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT04166734 2026-02-04

MESO-PRIME

Phase 1 Terminated

5 enrolled 13 charts

Other solid neoplasmThoracic

Mesothelioma

NCT03436056 2026-01-29

PRIMING

Phase 1 Terminated

2 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis

NCT04764474 2026-01-29

A Study of HMPL-306 in Advanced Hematological Malignancies With mIDH

Phase 1 Terminated

46 enrolled 29 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT05556616 2026-01-29

iinnovate-2

Phase 1 Terminated

15 enrolled 15 charts

Multiple Myeloma

NCT05787496 2026-01-28

A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

Phase 1 Terminated

28 enrolled 19 charts

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes, Recurrence, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic

NCT02408861 2026-01-21

Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Phase 1 Terminated

79 enrolled 24 charts

GastrointestinalSarcomaThoracic

Anus Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Sarcoma, Kaposi, HIV Infections

NCT04544995 2026-01-21

Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Paediatric Participants With Solid Tumors (SCOOP)

Phase 1 Terminated

47 enrolled 43 charts

Neoplasms, Neuroblastoma, Osteosarcoma

NCT06560632 2026-01-16

POLAR

Phase 1 Terminated

26 enrolled 14 charts

Other solid neoplasm

Advanced Solid Tumor

NCT03780725 2026-01-13

This Study Tests How BI 754111 is Distributed in Patients With Advanced Non-small Cell Lung Cancer or Patients With Head and Neck Cancer Who Are Treated With BI 754091

Phase 1 Terminated

8 enrolled 10 charts

Head & NeckThoracic

Carcinoma, Non-Small-Cell Lung, Head and Neck Neoplasms

NCT02948426 2026-01-08

Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Phase 1 Terminated

18 enrolled 19 charts

Carcinoma, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT05047536 2025-12-19

KZR-261 in Subjects With Advanced Solid Malignancies

Phase 1 Terminated

61 enrolled 25 charts

DermatologicGastrointestinalOther solid neoplasmThoracic

Uveal Melanoma, Melanoma, Mesothelioma, Neoplasm Metastasis, Colorectal Neoplasms

NCT03260504 2025-12-08

Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer

Phase 1 Terminated

6 enrolled 11 charts

Clear-cell metastatic renal cell carcinoma, Carcinoma, Renal Cell

NCT05147272 2025-12-05

Study of RP-6306 With Gemcitabine in Advanced Solid Tumors

Phase 1 Terminated

67 enrolled 22 charts

Other solid neoplasm

Adult Solid Tumor

NCT05147350 2025-12-05

MINOTAUR

Phase 1 Terminated

38 enrolled 17 charts

Other solid neoplasm

Advanced Solid Tumor

NCT05035407 2025-12-02

T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Phase 1 Terminated

36 enrolled 7 charts

Carcinoma, Neoplasm Metastasis, Triple Negative Breast Neoplasms

NCT06232408 2025-11-21

LIONS (PLK4 Inhibitor in Advanced Solid Tumors)

Phase 1 Terminated

29 enrolled 15 charts

Other solid neoplasm

Advanced Solid Tumor

NCT05980416 2025-11-14

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Phase 1 Terminated

88 enrolled 18 charts

Gastrointestinal

Adenocarcinoma, Digestive System Neoplasms, Gastrointestinal Neoplasms, Neoplasms, Neoplasms by Site, Stomach Neoplasms

NCT03770494 2025-11-04

A Study of LY3405105 in Participants With Advanced Cancer

Phase 1 Terminated

54 enrolled 26 charts

Other solid neoplasm

Solid Tumor

NCT02597036 2025-10-23

A Study of LY3127804 With Ramucirumab in Participants With Advanced Solid Tumors

Phase 1 Terminated

62 enrolled 25 charts

Other solid neoplasm

Solid Tumors

NCT04543188 2025-10-23

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Phase 1 Terminated

65 enrolled 52 charts

CNSDermatologicThoracic

Brain Diseases, Brain Neoplasms, Carcinoma, Non-Small-Cell Lung, Melanoma, Neoplasms, Central Nervous System Neoplasms

NCT05976334 2025-10-06

An Absorption, Distribution, Metabolism, Excretion (ADME) Study of [14C]Subasumstat in Adults With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

3 enrolled 19 charts

Other solid neoplasm

Solid Tumors

NCT06056310 2025-09-29

Phase 1b Safety Study of Xevinapant, Weekly Cisplatin, and RT in Participants With Unresected LA SCCHN (HyperlynX)

Phase 1 Terminated

18 enrolled 9 charts

Head and Neck Neoplasms, Laryngeal Diseases

NCT05168202 2025-09-25

A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromes

Phase 1 Terminated

56 enrolled 24 charts

MyeloidOther hematologic neoplasm

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute

NCT03307759 2025-09-15

SABRseq

Phase 1 Terminated

13 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT01198067 2025-09-04

Pomalidomide in Treating Patients With Relapsed or Refractory Waldenstrom Macroglobulinemia

Phase 1 Terminated

15 enrolled 12 charts

Waldenstrom Macroglobulinemia

NCT02784795 2025-08-21

A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors

Phase 1 Terminated

94 enrolled 28 charts

BreastGastrointestinalSarcoma

Breast Neoplasms, Colonic Neoplasms, Sarcoma, Cholangiocarcinoma

NCT05708924 2025-08-14

MT2021-27 FT538 Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Phase 1 Terminated

1 enrolled 5 charts

Fallopian Tube Neoplasms, Neoplasms, Ovarian Neoplasms

NCT04645797 2025-08-06

A Dose Escalation Study of APR003 in Patients With Advanced Colorectal Cancer (CRC) With Malignant Liver Lesions

Phase 1 Terminated

11 enrolled 25 charts

Gastrointestinal

Advanced Colorectal Carcinoma

NCT04904185 2025-07-25

ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma

Phase 1 Terminated

8 enrolled 8 charts

Melanoma

NCT03249792 2025-07-24

MK-2118-001

Phase 1 Terminated

140 enrolled 37 charts

Lymphoma

NCT05209152 2025-07-14

AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia

Phase 1 Terminated

7 enrolled 16 charts

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic

NCT04789408 2025-07-11

Study of KITE-222 in Participants With Relapsed/Refractory Acute Myeloid Leukemia

Phase 1 Terminated

15 enrolled 27 charts

Other hematologic neoplasm

Leukemia, Myeloid, Acute

NCT02675452 2025-07-09

AMG 176 First in Human Trial in Participants With Relapsed or Refractory Multiple Myeloma and Participants With Relapsed or Refractory Acute Myeloid Leukemia

Phase 1 Terminated

141 enrolled 46 charts

Other hematologic neoplasmPlasma cell

Multiple Myeloma, Recurrence, Leukemia, Myeloid, Acute