Clinical Trials Browser

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NCT01206465 2023-12-26

Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors

Phase 1 Completed

29 enrolled 12 charts

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT01336933 2023-09-22

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

Phase 2 Completed

34 enrolled 12 charts

Immunoblastic Lymphadenopathy, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic

NCT01947140 2022-11-23

PDX+Romi

Phase 1/2 Completed

DermatologicLymphoidOther hematologic neoplasmPlasma cell

Burkitt Lymphoma, Hodgkin Disease, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT01188876 2018-01-19

Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer

Phase 1/2 Completed

50 enrolled 15 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Recurrence

NCT01178944 2017-12-13

Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer

Phase 2 Completed

35 enrolled 11 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Stomach Neoplasms

NCT03356678 2017-11-29

Pralatrexate for Relapsed or Refractory Peripheral T-cell Lymphoma

Recurrence, Lymphoma, T-Cell, Peripheral

NCT01114282 2016-07-06

Phase I Bortezomib (VELCADE) in Combo With Pralatrexate in Relapsed/Refractory MM

Phase 1 Completed

Multiple Myeloma

NCT01532011 2016-07-04

Erlotinib in Combination With Pralatrexate in Advanced Malignancies

Phase 1 Completed

Other solid neoplasm

Advanced Cancers

NCT01129206 2016-06-01

Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy

Phase 2 Completed

6 enrolled 6 charts

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Squamous Cell Carcinoma, Adenocarcinoma, Esophageal Neoplasms

NCT01183065 2015-11-20

Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

Phase 2 Completed

13 enrolled 6 charts

Head and Neck Neoplasms

NCT00004238 2013-06-19

10-Propargyl-10-Deazaaminopterin in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms