Clinical Trials Browser

Phase 2 × NIH × 3-aminopyridine-2-carboxaldehyde thiosemicarbazone × Clear all

NCT05724108 2026-05-13

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Phase 2 Active not recruiting

Neuroendocrine Tumors

NCT00941070 2017-11-17

Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

Phase 2 Completed

26 enrolled 23 charts

Uterine Cervical Neoplasms, Vaginal Neoplasms

NCT00075504 2015-09-28

Triapine and Gemcitabine Hydrochloride in Gallbladder Cancer

Phase 2 Completed

33 enrolled 9 charts

Gastrointestinal

Gallbladder Neoplasms

NCT00381550 2015-01-06

3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia

Phase 2 Completed

35 enrolled 8 charts

MyeloidOther hematologic neoplasm

Pdgfra-Associated Chronic Eosinophilic Leukemia, Blast Crisis, Polycythemia Vera, Thrombocythemia, Essential, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myelomonocytic, Chronic, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT00054015 2013-11-06

3-AP in Treating Patients With Advanced Prostate Cancer

Phase 2 Completed

Prostatic Neoplasms

NCT00064064 2013-11-06

3-AP and Gemcitabine in Treating Patients With Metastatic Non-Small Cell Lung Cancer

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00077545 2013-10-08

3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction

Phase 2 Completed

Gastrointestinal

Adenocarcinoma Of Esophagus, Esophageal Neoplasms

NCT00085371 2013-10-08

Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT00064051 2013-08-02

3-AP and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancer

Phase 2 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT00077415 2013-05-15

3-AP and Gemcitabine as Second-Line Therapy in Treating Patients With Stage III or Stage IV Recurrent Non-Small Cell Lung Cancer

Phase 2 Completed

Adenocarcinoma of Lung, Adenocarcinoma, Bronchiolo-Alveolar, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00077350 2013-02-27

A Phase II Trial of Triapine (NSC #663249) in Combination With Gemcitabine as Second Line Treatment of Non-Small Cell Lung Cancer

Phase 2 Completed

Carcinoma, Non-Small-Cell Lung

NCT00081276 2013-01-24

3-AP and Cisplatin in Treating Patients With Recurrent or Persistent Platinum-Resistant Ovarian Epithelial or Primary Peritoneal Cancer

Phase 2 Completed

Carcinoma, Ovarian Epithelial

NCT00095888 2013-01-16

3-AP and Gemcitabine in Treating Patients With Refractory Metastatic Breast Cancer

Phase 2 Terminated

Breast Neoplasms, Breast Neoplasms, Male