Announcements Trials
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Phase

Phase 2 6Phase 1/2 5Phase 1 3Phase 2/3 1

Status

Completed 2Withdrawn 1Unknown 1Terminated 1Recruiting 1

Sponsor Class

OTHER 6INDUSTRY 4FED 1

Study Type

Interventional 6

Sponsor

Cancer Type

Thoracic 2Gastrointestinal 2Sarcoma 1Other solid neoplasm 1Dermatologic 1

Conditions

Small Cell Lung Carcinoma 1Sarcoma 1Resectable Hepatocellular Carcinoma 1Mesothelioma, Malignant 1Melanoma 1Carcinoma, Hepatocellular 1

Interventions

Cisplatin 1041Cyclophosphamide 973Carboplatin 954Radiotherapy 893Bevacizumab 847Gemcitabine 817pembrolizumab 759Paclitaxel 738Docetaxel 734Oxaliplatin 706Capecitabine 649Fluorouracil 564Rituximab 559Nivolumab 506Dexamethasone 487Etoposide 468Doxorubicin 458Irinotecan 442Drug Therapy 402Leucovorin 377Cytarabine 342Cetuximab 340Lenalidomide 326Trastuzumab 323Pemetrexed 315durvalumab 295Filgrastim 287Magnetic Resonance Spectroscopy 278Temozolomide 275Prednisone 274

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 2 × OTHER × ADI PEG20 × Clear all
NCT03449901 2025-12-11

ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma, Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung Cancer

Washington University School of Medicine

Phase 2 Completed
98 enrolled 12 charts
Sarcoma

Sarcoma

NCT06034977 2023-09-13

Phase 2 Study of ADI-PEG 20 Plus Lenvatinib Treatment in Subjects With Unresectable Hepatocellular Carcinoma

Chang Gung Memorial Hospital

Phase 2 Recruiting
120 enrolled
Gastrointestinal

Carcinoma, Hepatocellular

NCT04965714 2023-02-16

Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver Cancer

M.D. Anderson Cancer Center

Phase 2 Withdrawn
Gastrointestinal

Resectable Hepatocellular Carcinoma

NCT01266018 2022-10-25

Study of ADI-PEG 20 in Patients With Relapsed Sensitive or Refractory Small Cell Lung Cancer

Ludwig Institute for Cancer Research

Phase 2 Terminated
22 enrolled 14 charts
Thoracic

Small Cell Lung Carcinoma

NCT00450372 2017-02-08

Pegylated Arginine Deiminase in Treating Patients With Metastatic Melanoma That Cannot Be Removed by Surgery

University of Miami

Phase 2 Completed
38 enrolled 9 charts
Dermatologic

Melanoma

NCT01279967 2014-11-20

ADAM

Barts & The London NHS Trust

Phase 2 Unknown
70 enrolled
Other solid neoplasmThoracic

Mesothelioma, Malignant

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