Clinical Trials Browser

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT01089101 2026-04-13

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Phase 1/2 Active not recruiting

217 enrolled

CNS

Astrocytoma, Neurofibromatosis 1

NCT02813135 2026-01-16

ESMART

Phase 1/2 Recruiting

472 enrolled

Tumor-Agnostic

Neoplasms

NCT05309668 2025-12-18

SPRINKLE

Phase 1/2 Active not recruiting

36 enrolled 37 charts

CNS

Neurofibromatosis 1

NCT03581487 2025-11-05

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

Phase 1/2 Completed

40 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT06735820 2025-07-03

MEKMDM2

Phase 1/2 Not yet recruiting

45 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT03326388 2024-04-04

INSPECT

Phase 1/2 Completed

14 enrolled

CNS

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

NCT03705507 2023-05-11

SeluDex

Phase 1/2 Terminated

12 enrolled

LymphoidOther hematologic neoplasm

Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT02583542 2020-02-25

TORCMEK

Phase 1/2 Unknown

118 enrolled

Breast

Triple Negative Breast Neoplasms

NCT01752569 2019-02-20

SCART

Phase 1/2 Terminated

19 enrolled

Sarcoma

AIDS-related Kaposi sarcoma, Acquired Immunodeficiency Syndrome, Sarcoma, Kaposi

NCT02450656 2018-08-27

M14AFS

Phase 1/2 Unknown

320 enrolled

GastrointestinalThoracic

Carcinoma, Non-Small-Cell Lung, Gastrointestinal Neoplasms, Pancreatic Neoplasms, Colorectal Neoplasms

NCT02025114 2018-07-10

Selumetinib in Combination With Gefitinib in NSCLC Patients

Phase 1/2 Completed

34 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT01029418 2015-04-16

AZD6244 and Sorafenib in Advanced Hepatocellular Carcinoma

Phase 1/2 Terminated

30 enrolled

Gastrointestinal

Carcinoma, Hepatocellular, Liver Neoplasms

Clinical Trials

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

ESMART

SPRINKLE

Durvalumab, Tremelimumab, and Selumetinib in Treating Participants With Recurrent or Stage IV Non-small Cell Lung Cancer

MEKMDM2

INSPECT

SeluDex

TORCMEK

SCART

M14AFS

Selumetinib in Combination With Gefitinib in NSCLC Patients

AZD6244 and Sorafenib in Advanced Hepatocellular Carcinoma