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Phase

Phase 2 89Phase 1 44Phase 3 17Phase 1/2 12Phase 4 4Phase NA 2Phase EARLY_PHASE1 1Phase 2/3 1

Status

Completed 2Unknown 1Terminated 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

Thoracic 4

Conditions

Carcinoma, Non-Small-Cell Lung 3NRG1-fused Non-small Cell Lung Cancer 1

Interventions

Dexamethasone 56Metformin 50Cyclophosphamide 47Saline Solution 39Cytarabine 37Cisplatin 36Zoledronic Acid 34Letrozole 34Carboplatin 33Sodium Chloride 32Bupivacaine 31Docetaxel 30Bevacizumab 30Vincristine 29Methotrexate 29Fluorouracil 28Propofol 27Capecitabine 27Fentanyl 26Doxorubicin 26Rituximab 25Drug Therapy 25Dexmedetomidine 25Prednisone 23Paclitaxel 23Oxaliplatin 21Morphine 21Gemcitabine 21Radiotherapy 19Prednisolone 19

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 4 × Afatinib × Clear all
NCT04814056 2021-04-01

To Evaluate the Efficacy of Afatinib in the Treatment of Locally Advanced/Metastatic Non-Small Cell Lung Cancer With NRG1 Fusion

Shanghai Chest Hospital

Phase 4 Unknown
15 enrolled
Thoracic

NRG1-fused Non-small Cell Lung Cancer

NCT02514174 2020-03-30

Afatinib Treatment for Patients With EGFR Mutation Positive NSCLC Who Are Age 70 or Older

Boehringer Ingelheim

Phase 4 Completed
25 enrolled 13 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02208843 2018-12-17

Afatinib as Second-line Therapy for Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation

Boehringer Ingelheim

Phase 4 Completed
60 enrolled 10 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02695290 2017-09-18

Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3)

Boehringer Ingelheim

Phase 4 Terminated
1 enrolled 3 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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