Announcements Trials
Browse Landscape

Phase

Phase 3 2Phase 2 2Phase 4 1

Status

Completed 69Terminated 5Approved for marketing 3Unknown 2Active not recruiting 2No longer available 1Enrolling by invitation 1

Sponsor Class

OTHER 14INDUSTRY 5NETWORK 1

Study Type

Interventional 5

Sponsor

Cancer Type

Thoracic 2Head & Neck 2Tumor-Agnostic 1Genitourinary 1

Conditions

Head and Neck Neoplasms 2Neoplasms 1NSCLC Harboring NRG1 Fusion 1Carcinoma, Non-Small-Cell Lung 1

Interventions

pembrolizumab 184Carboplatin 130Paclitaxel 123Gemcitabine 122Docetaxel 96Cyclophosphamide 89Nivolumab 88Cisplatin 87Rituximab 71Dexamethasone 68Pemetrexed 64Bevacizumab 64Capecitabine 60atezolizumab 54fludarabine 49Azacitidine 49Fluorouracil 48130-nm albumin-bound paclitaxel 43venetoclax 41Trastuzumab 41Irinotecan 41Cetuximab 40Leucovorin 36Ipilimumab 36Erlotinib Hydrochloride 34Fulvestrant 32Cytarabine 32avelumab 31Oxaliplatin 31Albumin-Bound Paclitaxel 31

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Terminated × INDUSTRY × Afatinib × Clear all
NCT05588609 2026-04-27

Study Evaluating Zenocutuzumab in Patients With or Without Molecularly Defined Cancers

Partner Therapeutics, Inc.

Phase 2 Terminated
13 enrolled
GenitourinaryThoracic

NSCLC Harboring NRG1 Fusion

NCT00748709 2025-02-11

Phase II Trial of BIBW 2992 (Afatinib) in Genetically Pre-screened Cancers With EGFR and/or HER2 Gene Amplification.

Boehringer Ingelheim

Phase 2 Terminated
20 enrolled 11 charts
Tumor-Agnostic

Neoplasms

NCT02131155 2019-03-01

LUX-Head & Neck 4: Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

Boehringer Ingelheim

Phase 3 Terminated
36 enrolled 6 charts
Head & Neck

Head and Neck Neoplasms

NCT01345669 2017-12-07

LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

Boehringer Ingelheim

Phase 3 Terminated
617 enrolled 13 charts
Head & Neck

Head and Neck Neoplasms

NCT02695290 2017-09-18

Afatinib in EGFR+NSCLC (Recurrent or Stage IV) - Patients With Poor Performance Status (ECOG 2 or 3)

Boehringer Ingelheim

Phase 4 Terminated
1 enrolled 3 charts
Thoracic

Carcinoma, Non-Small-Cell Lung

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