NCT01872260 2026-04-01Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast CancerNovartisPhase 1/2 Active not recruiting255 enrolled
NCT05230810 2026-03-16Clinical Trial of Alpelisb and Tucatinib in Patients With PIK3CA-Mutant HER2+ Metastatic Breast Cancer.Criterium, Inc.Phase 1/2 Active not recruiting40 enrolled
NCT04997902 2025-12-23Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)Kura Oncology, Inc.Phase 1/2 Completed45 enrolled
NCT01602315 2020-12-29A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaNovartisPhase 1/2 Terminated179 enrolled 38 charts
NCT01708161 2018-09-13A Phase Ib/II Study of the Combination of BYL719 Plus AMG 479 in Adult Patients With Selected Solid TumorsNovartisPhase 1/2 Terminated47 enrolled 23 charts