Clinical Trials

23 enrolled

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT00318890 2019-02-05

Cisplatin and Docetaxel Plus Docetaxel and Radiotherapy With Amifostine for Squamous Cell Carcinoma of the Head and Neck

48 enrolled

Head and Neck Neoplasms

NCT03702985 2019-01-23

Radiation-protection Effect of Amifostine in Locally Advanced Rectal Cancer

160 enrolled

CNSGastrointestinalGenitourinaryGynecologicOther solid neoplasmSarcoma

Locally Advanced Rectal Cancer

NCT00003926 2017-11-29

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Phase 1 Terminated

13 enrolled

Ovarian Germ Cell Cancer, Astrocytoma, Brain Neoplasms, Chordoma, Ependymoma, Glioma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Hepatoblastoma, Desmoplastic Small Round Cell Tumor

NCT00503776 2017-06-20

Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia

Phase 2 Terminated

41 enrolled 12 charts

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Deglutition Disorders, Head and Neck Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Xerostomia, Mucositis

NCT00270790 2017-02-01

EVALUATION OF AMIFOSTINE FOR MUCOSAL AND HEMOPOETIC PROTECTION AND CARBOPLATIN, TAXOL, RADIOTHERAPY IN THE MANAGEMENT OF PATIENTS WITH HEAD AND NECK CANCER.(GCC 0202)

21 enrolled 6 charts

Head and Neck Neoplasms

NCT00571298 2017-01-23

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

Other solid neoplasmThoracic

141 enrolled

Mesothelioma, Malignant, Mesothelioma

NCT00003657 2017-01-20

High-dose ICE With Amifostine

CNSGenitourinaryGynecologicHead & NeckSarcomaThoracic

24 enrolled

AIDS-related Kaposi sarcoma, Testicular Germ Cell Tumor, Squamous Cell Carcinoma of Head and Neck, Carcinoma, Ovarian Epithelial, Urinary Bladder Neoplasms, Carcinoma, Non-Small-Cell Lung, Chondrosarcoma, Head and Neck Neoplasms, Kidney Neoplasms, Lung Neoplasms, Neoplasms, Unknown Primary, Ovarian Neoplasms, Sarcoma, Sarcoma, Kaposi, Osteosarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Esthesioneuroblastoma, Olfactory, Small Cell Lung Carcinoma

NCT00095927 2017-01-04

Randomized Amifostine For SCCHN

58 enrolled

Head & NeckOther

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Xerostomia, Mucositis

NCT00003582 2016-12-15

Radiation Therapy, Combination Chemotherapy, and Amifostine in Treating Patients With Head and Neck Cancer

36 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Neoplasms, Unknown Primary

NCT00006012 2016-07-06

Combination Chemotherapy and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

73 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00217438 2015-08-21

Melphalan and Amifostine Followed By One or Two Autologous or Syngeneic Stem Cell Transplants and Maintenance Therapy in Treating Patients With Stage II-III Multiple Myeloma

130 enrolled 6 charts

Plasma cell

Multiple Myeloma

NCT00012012 2015-01-07

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

45 enrolled 7 charts

Gynecologic

Uterine Cervical Neoplasms, Radiation Injuries

NCT00003313 2014-11-21

Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

243 enrolled

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00098683 2014-02-13

Amifostine in Treating Young Patients With Newly Diagnosed De Novo Myelodysplastic Syndromes

Classical hematologyMyeloid

10 enrolled

Anemia, Refractory, Anemia, Refractory, with Excess of Blasts, Myelodysplastic Syndromes, Myeloproliferative Disorders, Myelodysplastic-Myeloproliferative Diseases

NCT00004036 2013-12-19

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Phase 1 Unknown

30 enrolled

LymphoidMyeloidOther hematologic neoplasmOther neoplasmPlasma cell

Immunoglobulin Light-chain Amyloidosis, Blast Crisis, Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Leukemia, Hairy Cell, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Precancerous Conditions, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Biphenotypic, Acute, Leukemia, Prolymphocytic, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Primary Myelofibrosis, Drug-Related Side Effects and Adverse Reactions

NCT00003251 2013-12-04

Amifostine Plus Chemotherapy and Radiation Therapy in Treating Patients With Advanced, Unresectable Head and Neck Cancer

Phase 1/2 Unknown

46 enrolled

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Nasopharyngeal Neoplasms, Oropharyngeal Neoplasms, Radiation Injuries, Salivary Gland Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00003583 2013-12-04

Amifostine to Prevent Side Effects in Patients Who Are Receiving Chemotherapy and Radiation Therapy for Limited-Stage Small Cell Lung Cancer

20 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00003827 2013-12-04

Combination Chemotherapy in Treating Patients With Myelodysplastic Syndrome

Classical hematologyMyeloidOther hematologic neoplasm

25 enrolled

Anemia, Refractory, with Excess of Blasts, Leukemia, Myelodysplastic Syndromes

NCT00004264 2013-12-04

Docetaxel, Cisplatin, and Amifostine in Treating Patients With Advanced Non-small Cell Lung Cancer

Phase 1/2 Unknown

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00006105 2013-09-05

Gemcitabine, Cisplatin, and Amifostine Following Surgery in Treating Patients With Locally Advanced Bladder Cancer

37 enrolled

Genitourinary

Urinary Bladder Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT01586117 2013-08-15

A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity

40 enrolled

Rectal Neoplasms

NCT00003268 2013-08-02

Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Other hematologic neoplasm

Leukemia, Erythroblastic, Acute, Leukemia, Leukemia, Megakaryoblastic, Acute, Leukemia, Monocytic, Acute, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Acute, Drug-Related Side Effects and Adverse Reactions

NCT00003089 2013-07-10

Chemotherapy, Amifostine, and Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer

Adenocarcinoma of Lung, Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00058071 2013-07-09

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

100 enrolled

Gynecologic

Hydatidiform Mole, Peripheral Nervous System Diseases, Neurotoxicity Syndromes, Gestational Trophoblastic Disease

NCT00003811 2013-07-04

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

27 enrolled

GenitourinaryGynecologic

Ovarian Germ Cell Cancer, Ovarian Neoplasms, Teratoma, Testicular Neoplasms, Drug-Related Side Effects and Adverse Reactions

NCT00004919 2013-07-02

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

30 enrolled

Other solid neoplasm

Unspecified Childhood Solid Tumor, Protocol Specific

NCT00003555 2013-06-26

Paclitaxel Plus Chemoprotection With Amifostine in Treating Patients With Recurrent or Refractory Solid Tumors

20 enrolled

Other solid neoplasm

Unspecified Adult Solid Tumor, Protocol Specific

NCT00003580 2013-06-26

Amifostine to Treat Side Effects of Treatment in Patients Receiving Radiation Therapy and Cisplatin for Advanced Head and Neck Cancer

Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00003994 2013-06-14

Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

277 enrolled

Hepatoblastoma

NCT00004176 2013-05-16

Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer

34 enrolled

Lung Neoplasms, Radiation Injuries, Drug-Related Side Effects and Adverse Reactions

NCT00217542 2013-05-03

Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery

DermatologicGenitourinary

42 enrolled

Carcinoma, Renal Cell, Melanoma

NCT00003425 2013-04-26

Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect