NCT06948552 2026-04-01
Photodynamic Diagnosis of Upper Tract Urothelial Carcinoma Using Fluorescence Endoscopy and Oral 5-ALA
Henry Ford Health System
Phase 2 Recruiting
Clinical Trials
73 trialsNCT06876038 2026-03-19
Low-cost Screening and Image-guided Photodynamic Therapy (PDT) of Premalignant and Malignant Oral Lesions
University of Massachusetts, Boston
Phase 2 Not yet recruiting
NCT06665724 2026-02-27
Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)
Universität Münster
Phase 1 Completed
NCT07038278 2026-02-27
5-ALARMS
University of Colorado, Denver
Phase EARLY_PHASE1 Not yet recruiting
NCT07076472 2026-02-23
Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma
Mayo Clinic
Phase EARLY_PHASE1 Recruiting
NCT05923060 2026-02-20
Imaging Techniques to Monitor Photosensitizer and sO2 Levels During Photodynamic Therapy of Actinic Keratoses
Case Comprehensive Cancer Center
Phase 2 Completed
NCT06307548 2026-02-10
Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer
Roswell Park Cancer Institute
Phase 1/2 Suspended
NCT07201376 2026-02-06
PPIX
Dartmouth-Hitchcock Medical Center
Recruiting
NCT06623201 2026-01-29
Blue-Light Photodynamic Therapy and Sonidegib for Multiple Basal Cell Carcinomas
US Dermatology Partners, Phoenix
Phase 1 Recruiting
NCT06907485 2026-01-21
A Multicenter Study to Assess the Feasibility of 5-Aminolevulinic Acid (5-ALA) in Pediatric Brain Tumor Patients
University of Pittsburgh
Phase 2 Not yet recruiting
NCT07053852 2026-01-02
Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage
Rochester Dermatologic Surgery
Phase 1 Completed
NCT04738162 2025-12-10
Clinical Safety Study on 5-Aminolevulinic Acid (5-ALA) in Children and Adolescents With Brain Tumors
Universität Münster
Phase 2 Completed
NCT05020912 2025-11-26
Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy
Case Comprehensive Cancer Center
Phase 2 Recruiting
NCT06027619 2025-10-23
Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses
Case Comprehensive Cancer Center
Phase 2 Completed
NCT02191488 2025-09-15
ALA-induced PpIX Fluorescence During Brain Tumor Resection
Dartmouth-Hitchcock Medical Center
Phase 1 Active not recruiting
NCT02691923 2025-08-03
Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
Dartmouth-Hitchcock Medical Center
Phase 2 Recruiting
NCT05101798 2025-07-28
The Role of 5-Aminolevulinic Acid Fluorescence-Guided Surgery in Head and Neck Cancers: a Pilot Trial
Icahn School of Medicine at Mount Sinai
Phase 2 Terminated
NCT02728388 2025-05-08
Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II
Medical College of Wisconsin
Phase 2 Recruiting
NCT04469699 2025-03-11
NOA11
University Hospital Muenster
Phase 2 Terminated
NCT06159842 2025-02-12
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (isSCC)
The Center for Clinical and Cosmetic Research
Phase 2 Completed
NCT03066843 2025-01-31
Photodynamic Therapy Incubation Times for Actinic Keratosis
Northwestern University
Phase NA Active not recruiting
NCT06745999 2024-12-24
Cryotherapy in Combination with Red Light PDT for Actinic Keratosis of Full Face
Psoriasis Treatment Center of Central New Jersey
Phase 4 Unknown
NCT05590689 2024-12-16
ALA-RDTinGBM
Universität Münster
Phase 1/2 Recruiting
NCT04845919 2024-11-12
Sonic ALA
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Phase 2 Completed
NCT06577311 2024-08-29
Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
The Center for Clinical and Cosmetic Research
Phase 2 Recruiting
NCT06252727 2024-08-15
Fluorescent Aided Resection and Evaluation of Soft Tissue Sarcomas (FLARES)
University of California, Davis
Phase 1 Withdrawn
NCT03963102 2024-07-26
Duration of Ameluz Application in Acral Actinic Keratoses Response
Royal Cornwall Hospitals Trust
Phase 4 Terminated
NCT03327831 2024-06-27
Study of Daylight Photodynamic Therapy With Aminolevulinic Acid for Actinic Keratoses
University of California, Irvine
Phase 4 Completed
NCT01128218 2023-11-30
A Study of the Specificity and Sensitivity of 5- Aminolevulinic Acid (ALA) Fluorescence in Malignant Brain Tumors
Southern Illinois University
Phase 1/2 Completed
NCT01502280 2023-11-24
BALANCE
St. Joseph's Hospital and Medical Center, Phoenix
Phase 3 Completed
NCT05850377 2023-05-09
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas
Sociedad de Lucha Contra el Cáncer del Ecuador
Not yet recruiting
NCT03109353 2023-01-13
Modification of Extracorporeal Photopheresis in Cutaneous T-cell Lymphoma or Chronic Graft-versus-host Disease
St. Olavs Hospital
Phase 1/2 Completed
NCT03281811 2023-01-05
Photodynamic Therapy in Treating Patients With Refractory Mycosis Fungoides
Mayo Clinic
Phase EARLY_PHASE1 Completed
NCT04055688 2022-05-31
Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas
H. Lee Moffitt Cancer Center and Research Institute
Completed
NCT03322293 2022-03-09
Daylight Photodynamic Therapy for Actinic Keratosis
University of California, San Francisco
Phase 1 Completed
NCT02751151 2021-10-06
PDT
Inova Health Care Services
Phase NA Completed
NCT00752323 2021-09-17
Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma
Case Comprehensive Cancer Center
Phase 2 Completed
NCT01682811 2021-06-18
Phase I Photodynamic Therapy (PDT) for Benign Dermal Neurofibromas (NF1)
Medical College of Wisconsin
Phase 1 Completed
NCT04390802 2021-02-24
A Pilot Study of 5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Pituitary Adenomas
Massachusetts General Hospital
Unknown
NCT03638622 2021-02-21
UH3-India
Massachusetts General Hospital
Phase 1/2 Completed
NCT02867722 2021-02-01
DaylightPDT
Brigham and Women's Hospital
Phase NA Withdrawn
NCT01556009 2020-11-02
Vismodegib
UCSF Benioff Children's Hospital Oakland
Phase 2 Completed
NCT02157623 2020-07-30
Blue vs Red Light During Levulan Based Photodynamic Therapy in Patients With Basal Cell Nevus Syndrome
The Cleveland Clinic
Phase NA Completed
NCT00977795 2019-09-10
A Study of the Specificity and Sensitivity of 5-ALA Fluorescence in Malignant Brain Tumors
Endeavor Health
Phase 1/2 Withdrawn
NCT02464709 2019-08-28
Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)
Joint Authority for Päijät-Häme Social and Health Care
Phase 4 Completed
NCT00870779 2019-06-14
FGR
Dartmouth-Hitchcock Medical Center
Phase 1 Completed
NCT00978081 2019-04-23
Photodynamic Therapy in Treating Patients With Premalignant or Early Stage Head and Neck Tumors
Abramson Cancer Center at Penn Medicine
Phase 1 Completed
NCT00961090 2019-04-12
Safety Study of Aminolevulinic Acid (ALA) to Improve Visibility of Brain Tumors During Surgery
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Phase 2 Completed
NCT02367547 2019-03-28
Superficial Basal Cell Cancer's Photodynamic Therapy: Comparing Three Photosensitizers: HAL and BF-200 ALA Versus MAL
Joint Authority for Päijät-Häme Social and Health Care
Phase 1/2 Unknown
NCT03642535 2019-03-19
Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention
Shanghai Dermatology Hospital
Phase 4 Unknown