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Phase

Phase 1 2Phase 3 1Phase 2 1Phase 1/2 1

Status

Completed 3Withdrawn 1Recruiting 1

Sponsor Class

INDUSTRY 4OTHER 1

Study Type

Interventional 5

Sponsor

Cancer Type

Other hematologic neoplasm 2Sarcoma 1Plasma cell 1Other neoplasm 1Myeloid 1Lymphoid 1

Conditions

Neoplasms 3Thrombocythemia, Essential 1Primary Myelofibrosis 1Preleukemia 1Precancerous Conditions 1Peripheral Nervous System Neoplasms 1Neurofibrosarcoma 1Neoplasms by Histologic Type 1Myeloproliferative Disorders 1Myelodysplastic-Myeloproliferative Diseases 1Myelodysplastic Syndromes 1Multiple Myeloma 1Lymphoma 1Leukemia, Myeloid, Acute 1Leukemia 1Hematologic Neoplasms 1Hematologic Diseases 1Bone Marrow Diseases 1

Interventions

Cyclophosphamide 3155Cisplatin 3151Carboplatin 2929Paclitaxel 2671Radiotherapy 2643Gemcitabine 2544pembrolizumab 2324Docetaxel 2154Bevacizumab 2126Fluorouracil 1819Capecitabine 1780Oxaliplatin 1709Dexamethasone 1589Nivolumab 1516Doxorubicin 1477Rituximab 1453Etoposide 1341Magnetic Resonance Spectroscopy 1261Irinotecan 1232Leucovorin 1212Cytarabine 1123Pemetrexed 1060Drug Therapy 1060fludarabine 1044Vincristine 956Specimen Handling 928Prednisone 924Cetuximab 919Lenalidomide 916Trastuzumab 897

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Interventional × CPI-0610 × Clear all
NCT02158858 2025-10-08

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Constellation Pharmaceuticals

Phase 1/2 Completed
336 enrolled
MyeloidOther hematologic neoplasmOther neoplasm

Bone Marrow Diseases, Hematologic Diseases, Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasms, Neoplasms by Histologic Type, Precancerous Conditions, Preleukemia, Thrombocythemia, Essential, Leukemia, Myeloid, Acute, Myelodysplastic-Myeloproliferative Diseases, Primary Myelofibrosis

NCT06401356 2025-06-22

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

Novartis

Phase 3 Recruiting
50 enrolled
Other hematologic neoplasm

Hematologic Neoplasms

NCT01949883 2024-05-08

A Phase 1 Study Evaluating CPI-0610 in Patients With Progressive Lymphoma

Constellation Pharmaceuticals

Phase 1 Completed
64 enrolled
Lymphoid

Lymphoma, Neoplasms

NCT02157636 2024-04-18

A Phase 1 Study Evaluating CPI-0610 in Patients With Previously Treated Multiple Myeloma

Constellation Pharmaceuticals

Phase 1 Completed
30 enrolled
Plasma cell

Multiple Myeloma, Neoplasms

NCT02986919 2018-09-11

Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors

University of Texas Southwestern Medical Center

Phase 2 Withdrawn
Sarcoma

Peripheral Nervous System Neoplasms, Neurofibrosarcoma

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