Clinical Trials

Phase EARLY_PHASE1 Recruiting

55 enrolled

Other solid neoplasm

Solid Tumor

NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

15 enrolled

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT04093323 2026-02-25

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

Phase 2 Terminated

1 enrolled

Dermatologic

Melanoma

NCT01356290 2026-02-23

MEMMAT

232 enrolled

Phase EARLY_PHASE1 Completed

Ependymoma, Medulloblastoma, Recurrence

NCT01881048 2026-01-29

Window of Opportunity Study Targeting the Inflammatory Milieu

42 enrolled

Breast Neoplasms

NCT07174570 2026-01-28

Celecoxib, Durvalumab and Tremelimumab for the Treatment of Patients With Advanced or Metastatic Liver Cancer

39 enrolled

Phase 1 Active not recruiting

Carcinoma, Hepatocellular

NCT06076837 2026-01-12

The Seven Trial: Exploiting the Unfolded Protein Response

6 enrolled

Pancreatic Cancer Metastatic

NCT03926338 2025-11-20

PICC

270 enrolled

Turcot syndrome, Colorectal Neoplasms

NCT07154316 2025-09-04

Phase II RCT of LCRT vs SCRT + CAPOX/PD-1i/COX-2i in MSS Locally Advanced Rectal Cancer

138 enrolled

Colorectal Neoplasms

NCT07150949 2025-09-02

Long-course Chemoradiotherapy or Short-course Radiotherapy Combined With CAPOX, PD-1antibody, and COX-2 Inhibitor for MSS Locally Advanced Rectal Cancer (SERRAC)

138 enrolled

Locally Advanced Rectal Cancer

NCT07104266 2025-08-05

Triple Negative Breast Cancer and Celecoxib. Pilot Study

30 enrolled

Triple Negative Breast Neoplasms

NCT02885974 2025-07-28

BLAST

22 enrolled

Genitourinary

Urinary Bladder Neoplasms

NCT05756166 2025-06-24

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

Phase 1/2 Terminated

5 enrolled

Triple Negative Breast Neoplasms

NCT02432378 2025-06-19

Intensive Locoregional Chemoimmunotherapy for Recurrent Ovarian Cancer Plus Intranodal DC Vaccines

Phase 1/2 Terminated

25 enrolled

Gynecologic

Ovarian Neoplasms

NCT06722534 2025-05-30

Celecoxib for Prevention of Progression in Peutz-Jeghers Syndrome

Phase NA Recruiting

80 enrolled

Peutz-Jeghers Syndrome

NCT02030964 2025-02-17

DFMO

30 enrolled

Neuroblastoma

NCT04162873 2025-02-12

Celecoxib Through Surgery and Radiation Therapy for the Treatment of Advanced Head and Neck Cancer

Phase 2 Terminated

13 enrolled 36 charts

Head & Neck

Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms, Paranasal Sinus Neoplasms

NCT03084536 2024-12-24

PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery

134 enrolled 9 charts

Breast Neoplasms

NCT05281276 2024-12-20

Chidamide + Celecoxib in Advanced Metastatic Colorectal Cancer (CCmCC)

9 enrolled

Colorectal Neoplasms

NCT03643744 2024-12-19

Photodynamic Therapy-Induced Immune Modulation: Part III

12 enrolled 9 charts

Dermatologic

Keratosis, Actinic

NCT04176419 2024-11-12

Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery

Phase 3 Terminated

30 enrolled

Head & Neck

Head and Neck Neoplasms

NCT06545526 2024-08-09

Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis

Phase 3 Recruiting

28 enrolled

Adenomatous Polyposis Coli

NCT02641314 2024-05-10

METRO-NB2012

18 enrolled

Neuroblastoma

NCT03878524 2024-03-04

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

BreastClassical hematologyGastrointestinalGenitourinaryLymphoidMyeloidOther hematologic neoplasmPlasma cell

2 enrolled

Anemia, Blast Crisis, Breast Neoplasms, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Neoplasm Metastasis, Pancreatic Neoplasms, Prostatic Neoplasms, Thrombocytosis, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Hematologic Neoplasms, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Primary Myelofibrosis

NCT03728179 2024-02-20

RACIN

40 enrolled

Other solid neoplasm

Solid Tumor, Adult

NCT05578287 2023-12-07

DETECT

Phase 2 Unknown

29 enrolled

Colorectal Neoplasms

NCT01545141 2023-10-27

Chemokine-Modulatory Regimen for Recurrent Resectable Colorectal Cancer

Phase 1/2 Terminated

15 enrolled 9 charts

Neoplasm Metastasis, Recurrence, Colorectal Neoplasms

NCT00665457 2023-09-13

Biomarkers in Women Receiving Chemotherapy & Celecoxib for Stage II or Stage III Breast Cancer Removable by Surgery

Phase 2 Terminated

3 enrolled 6 charts

Breast Neoplasms

NCT04081389 2023-09-11

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

9 enrolled 17 charts

Breast Carcinoma In Situ, Breast Neoplasms, Triple Negative Breast Neoplasms

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

9 enrolled 9 charts

Phase EARLY_PHASE1 Completed

Neurofibroma, Neurofibromatosis 1

NCT03599453 2023-07-18

Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer

8 enrolled

Triple Negative Breast Neoplasms

NCT00538031 2023-04-21

Cyclophosphamide With or Without Celecoxib in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

52 enrolled 10 charts

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms

NCT01285817 2023-03-13

SFCE METRO 01

79 enrolled

Survival Without Progression

NCT00503035 2023-02-13

Molecular Targeting of 15-Lipoxygenase-1 (15-LOX-1) for Apoptosis Induction in Human Colorectal Cancers

51 enrolled 10 charts

Adenomatous Polyposis Coli, Colorectal Neoplasms

NCT05327751 2022-04-14

HFS

Phase 3 Unknown

44 enrolled

Colorectal Neoplasms, Hand-Foot Syndrome

NCT03403634 2022-03-02

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

19 enrolled 15 charts

Colorectal Neoplasms

NCT02484664 2022-01-20

COLA

12 enrolled 11 charts

Lymphangioleiomyomatosis

NCT00112502 2021-10-18

Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme

178 enrolled 23 charts

CNSSarcoma

Glioblastoma, Central Nervous System Neoplasms, Gliosarcoma

NCT02770378 2021-10-05

A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma

Phase 1/2 Completed

10 enrolled

Glioblastoma

NCT03645187 2021-04-20

Celecoxib as Adjuvant Therapy to Chemotherapy in Patients With Metastatic Colorectal Cancer

Phase 4 Unknown

50 enrolled

Colon Cancer Stage

NCT00020878 2020-08-03

Celecoxib in Preventing Non-Small Cell Lung Cancer in Tobacco Smokers

21 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00062179 2020-08-03

Paclitaxel and Carboplatin With or Without Celecoxib Before Surgery in Treating Patients With Stage IIIA Non-Small Cell Lung Cancer

7 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT00075673 2020-07-27

Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer

6 enrolled