Announcements Trials
Browse Landscape

Phase

Phase 1 4Phase 1/2 3Phase 2 1

Status

Active not recruiting 2Unknown 1Completed 1

Sponsor Class

INDUSTRY 3OTHER 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4Thoracic 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Glioma 3Glioblastoma 3Pancreatic Neoplasms 1Oligodendroglioma 1Melanoma 1Colorectal Neoplasms 1Carcinoma, Non-Small-Cell Lung 1Breast Neoplasms 1Brain Neoplasms 1Astrocytoma 1

Interventions

Cyclophosphamide 624pembrolizumab 500Paclitaxel 456Gemcitabine 438Carboplatin 435Cisplatin 418Radiotherapy 380fludarabine 365Nivolumab 340Docetaxel 277Bevacizumab 276Irinotecan 257Magnetic Resonance Spectroscopy 242Fluorouracil 228Dexamethasone 225Specimen Handling 221Capecitabine 218Rituximab 205Cytarabine 201Oxaliplatin 200Ipilimumab 199Temozolomide 197Biopsy 196fludarabine phosphate 194Etoposide 181Lenalidomide 176Doxorubicin 175Leucovorin 173Cetuximab 171Injections 170

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Interventional × Chlorotoxin × Clear all
NCT05627323 2026-01-29

CAR T Cells in Patients With MMP2+ Recurrent or Progressive Glioblastoma

Chimeric Therapeutics

Phase 1 Active not recruiting
42 enrolled
CNS

Glioblastoma

NCT04214392 2025-10-06

Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma

City of Hope Medical Center

Phase 1 Active not recruiting
19 enrolled
CNS

Glioblastoma, Glioma

NCT00591058 2009-07-17

Safety and Dose-Finding Study of TM-601 in Adults With Recurrent Malignant Glioma

TransMolecular

Phase 1 Unknown
36 enrolled
CNS

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00379132 2009-03-31

131-I-TM-601 Study in Adults With Solid Tumors

TransMolecular

Phase 1 Completed
60 enrolled
BreastCNSDermatologicGastrointestinalThoracic

Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Glioma, Melanoma, Pancreatic Neoplasms, Colorectal Neoplasms

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