Clinical Trials Browser

Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, T-Cell, Lymphoma, Large B-Cell, Diffuse, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell

NCT07447414 2026-04-16

LUBRECA

Phase NA Recruiting

140 enrolled

Breast

Breast Neoplasms

NCT04693377 2026-04-15

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Phase NA Recruiting

40 enrolled

DermatologicGastrointestinalGenitourinaryHead & NeckSarcoma

Carcinoma, Renal Cell, Carcinoma, Transitional Cell, Melanoma, Neoplasm Metastasis, Prostatic Neoplasms, Sarcoma, Thyroid Neoplasms, Colorectal Neoplasms

Clinical Trials

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Cryoablation+Ipilimumab+Nivolumab in Melanoma

Improving Cryoablation Efficacy With BARRigel Rectal Spacing (ICE-BARR)

Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma

LUBRECA

Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial

Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer

CRYO-1

SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors

Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease

Stereotactic Guided Biopsy and Cryoablation

NAP-C/R

Cryoablation for the Treatment of Metastatic Cancer

Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial

CRYOMUNE

Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma

Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules

Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function

CRYODESMO-02

LOGIC

Study of Cryoablation and Nirogacestat for Desmoid Tumor

Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC

CASTLE-ZS-02

ColdPlay2

CRYSTAL - SIX

Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma

Thermal Ablation of Cervical Metastases From Thyroid Carcinoma

Cryoablation Combined with Sintilimab Plus Lenvatinib in Previously Treated Unresectable Liver Metastasis from Solid Tumors

CASTLE-11

Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma

A Clinical Study of the Cryoablation Technique for Peripheral Lung Malignancies

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer

A Study of Pre-Operative Treatment With Cryoablation and Immune Therapy in Early Stage Breast Cancer

Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in NSCLC

Cryoablation with or Without Serplulimab in Treating Patients with Stage I-IIA Non-small Cell Lung Cancer

Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma

Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma

Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy

Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases

Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma

Subzero and Scorpion Trial

Cryoablation of Bone Metastases From Endocrine Tumors

CASTLE-09

CASTLE-10

ROAST

CASTLE-08

DCIS

To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study)