Clinical Trials

9 enrolled

Genitourinary

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell

NCT02534233 2025-08-01

ColdPlay2

58 enrolled 10 charts

Barrett Esophagus, Esophageal Neoplasms

NCT02380443 2025-05-16

AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer

13 enrolled 8 charts

Neoplasm Metastasis, Colorectal Neoplasms

NCT05010668 2025-02-21

Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma

28 enrolled

Cholangiocarcinoma

NCT05302921 2025-01-01

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

CNSDermatologicGastrointestinalGenitourinarySarcoma

5 enrolled

Carcinoma, Hepatocellular, Melanoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma

NCT02833233 2024-10-23

A Study of Pre-Operative Treatment With Cryoablation and Immune Therapy in Early Stage Breast Cancer

5 enrolled 8 charts

Breast

Breast Neoplasms

NCT03290677 2024-03-18

Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy

30 enrolled

Lung Neoplasms

NCT04118166 2023-12-12

Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma

30 enrolled 9 charts

Sarcoma

NCT00002997 2023-06-15

Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer

Colonic Neoplasms, Neoplasm Metastasis, Rectal Neoplasms, Colorectal Neoplasms

NCT02821754 2023-03-28

A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

54 enrolled 14 charts

Diabetes Mellitus, Insulin-Dependent, 12, Bile Duct Neoplasms, Biliary Tract Neoplasms, Carcinoma, Hepatocellular, Liver Neoplasms, Cholangiocarcinoma

NCT05727813 2023-02-14

To Detect Cryoimmunologic Response Induced by Early Breast Cancer Ultrasound-guided Cryoablation (ICE-study)

20 enrolled

Breast

Breast Neoplasms, Neoplasms, Second Primary

NCT02085941 2022-08-15

Image-guided Cryoablation of Head, Neck and Spine Tumors

Phase EARLY_PHASE1 Completed

30 enrolled 10 charts

CNSHead & Neck

Head and Neck Neoplasms, Spinal Cord Neoplasms

NCT02626130 2022-07-07

Tremelimumab With or Without Cryoablation in Treating Patients With Metastatic Kidney Cancer

29 enrolled

Genitourinary

Carcinoma, Renal Cell

NCT01293448 2022-04-28

Evaluation of Balloon-based Cryoablation of Human Esophageal Epithelium

21 enrolled

Barrett Esophagus, Esophageal Neoplasms

NCT02489357 2021-11-12

Pembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer

12 enrolled 5 charts

Genitourinary

Prostatic Neoplasms

NCT00731341 2021-07-19

Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata

3 enrolled 10 charts

Leiomyoma, Menorrhagia

NCT01307501 2021-07-19

ECLIPSE

40 enrolled 19 charts

Lung Neoplasms, Neoplasm Metastasis, Neoplasms

NCT01957787 2021-07-19

SOLSTICE

131 enrolled 20 charts

Lung Neoplasms, Neoplasm Metastasis

NCT02511678 2021-07-19

MOTION

73 enrolled 15 charts

Neoplasm Metastasis, Pain

NCT01461265 2021-07-16

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

Phase 1 Completed

29 enrolled

Sarcoma

Bone Neoplasms, Neoplasm Metastasis, Pain

NCT02736760 2020-11-09

Daylight-PDT With MAL for AK and Photodamaged Skin

Phase 4 Completed

58 enrolled

Dermatologic

Keratosis, Actinic

NCT02576106 2020-10-22

CRYOSE01

22 enrolled

Breast

Carcinoma, Ductal, Breast

NCT00303901 2020-07-22

Cryotherapy in Treating Patients With Primary Lung Cancer or Lung Metastases That Cannot Be Removed By Surgery

40 enrolled 7 charts