NCT07447414 2026-04-16
LUBRECA
Hospital Universitario Lucus Augusti
Phase NA Recruiting
Clinical Trials
126 trialsNCT04248582 2026-04-15
Cryotherapy for Locally Advanced Esophageal Cancer
Hunter Holmes Mcguire Veteran Affairs Medical Center
Phase 1 Active not recruiting
NCT04693377 2026-04-15
Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial
M.D. Anderson Cancer Center
Phase NA Recruiting
NCT03546686 2026-03-27
Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Triple-negative Breast Cancer
University of Texas Southwestern Medical Center
Phase 2 Active not recruiting
NCT07398118 2026-03-23
CRYO-1
St. Antonius Hospital
Phase NA Not yet recruiting
NCT07450352 2026-03-04
SEED-CRYO: Sequential 125I Seed Implantation Followed by Cryoablation vs Single-Modality Local Therapy in Unresectable Solid Tumors
Jinan Military General Hospital
Phase 2 Not yet recruiting
NCT07437625 2026-02-27
Lesion-Allocated Therapy for Multiple Metastases and Tumor-Zoned Treatment for Bulky Tumors: A Phase II Study of Iodine-125 Seed Implantation Combined With Cryoablation in High-Burden Metastatic Disease
Jinan Military General Hospital
Phase 2 Not yet recruiting
NCT07439432 2026-02-27
Stereotactic Guided Biopsy and Cryoablation
Montefiore Medical Center
Phase NA Withdrawn
NCT07416448 2026-02-18
NAP-C/R
Ukrainian Society of Regional Anesthesia and Pain Therapy
Phase NA Recruiting
NCT04150939 2026-02-17
Cryoablation for the Treatment of Metastatic Cancer
M.D. Anderson Cancer Center
Phase NA Active not recruiting
NCT06593106 2026-02-02
Cryodevitalization for the Treatment of Early Stage Lung Cancer, CRYSTAL Trial
Vanderbilt-Ingram Cancer Center
Phase NA Recruiting
NCT04339218 2026-01-30
CRYOMUNE
Institut Bergonié
Phase 3 Recruiting
NCT04701918 2026-01-22
Cryoablation With Pembrolizumab Or Avelumab In Urothelial Carcinoma
Massachusetts General Hospital
Phase 2 Completed
NCT07232433 2026-01-22
Safety and Efficacy Evaluation of Cryoablation in the Treatment of Ground-Glass Nodules
Ruijin Hospital
Phase NA Recruiting
NCT05779423 2026-01-06
Cryoablation+Ipilimumab+Nivolumab in Melanoma
Massachusetts General Hospital
Phase 2 Recruiting
NCT07306286 2025-12-29
Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy
Ruijin Hospital
Phase 2 Recruiting
NCT07272356 2025-12-09
Evaluation of Efficacy of Minimally Invasive Local Therapy for Lung Tumors and Its Impact on Breathing Function
Lithuanian University of Health Sciences
Phase NA Active not recruiting
NCT06081400 2025-11-19
CRYODESMO-02
University Hospital, Strasbourg, France
Phase NA Recruiting
NCT05806385 2025-09-09
LOGIC
Texas Tech University Health Sciences Center
Phase 1/2 Not yet recruiting
NCT05949099 2025-09-08
Study of Cryoablation and Nirogacestat for Desmoid Tumor
Stanford University
Phase 2 Recruiting
NCT06127303 2025-09-05
Toripalimab Combined With Cryoablation for First-line Oligo-progression in Driver-negative Advanced NSCLC
Shanghai Chest Hospital
Phase 2 Recruiting
NCT07070700 2025-08-12
CASTLE-ZS-02
Fudan University
Phase 2 Recruiting
NCT02534233 2025-08-01
ColdPlay2
Johns Hopkins University
Phase NA Completed
NCT06839001 2025-06-26
CRYSTAL - SIX
Hospital do Coracao
Phase 3 Recruiting
NCT03325101 2025-06-12
Dendritic Cell Therapy With Pembrolizumab for Metastatic or Unresectable Melanoma
Mayo Clinic
Phase 1/2 Terminated
NCT06246968 2025-05-21
A Study of Pembrolizumab and Cryoablation in People With Breast Cancer
Memorial Sloan Kettering Cancer Center
Phase 1 Recruiting
NCT02380443 2025-05-16
AlloStim® Immunotherapy Dosing Alone or in Combination With Cryoablation in Metastatic Colorectal Cancer
Mirror Biologics, Inc.
Phase 2 Completed
NCT03035331 2025-05-16
Dendritic Cell Therapy, Cryosurgery, and Pembrolizumab in Treating Patients With Non-Hodgkin Lymphoma
Mayo Clinic
Phase 1/2 Completed
NCT04522570 2025-04-30
Thermal Ablation of Cervical Metastases From Thyroid Carcinoma
Instituto do Cancer do Estado de São Paulo
Phase NA Active not recruiting
NCT05098847 2025-02-27
Cryoablation Combined with Sintilimab Plus Lenvatinib in Previously Treated Unresectable Liver Metastasis from Solid Tumors
Fudan University
Phase 2 Recruiting
NCT06032845 2025-02-27
CASTLE-11
Fudan University
Phase 2 Recruiting
NCT05010668 2025-02-21
Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Advanced Intrahepatic Cholangiocarcinoma
Fudan University
Phase 2 Completed
NCT06832969 2025-02-18
A Clinical Study of the Cryoablation Technique for Peripheral Lung Malignancies
Guangzhou Medical University
Phase NA Not yet recruiting
NCT05302921 2025-01-01
Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
Children's National Research Institute
Phase 2 Completed
NCT06178354 2024-12-16
Focal Ablation With Focal Cryotherapy or HIFU for the Treatment of Men With Localized Prostate Cancer
University of California, Davis
Phase NA Recruiting
NCT02833233 2024-10-23
A Study of Pre-Operative Treatment With Cryoablation and Immune Therapy in Early Stage Breast Cancer
Memorial Sloan Kettering Cancer Center
Phase NA Completed
NCT06483009 2024-08-30
Efficacy and Safety of Combination Therapy of Sintilimab and Chemotherapy With Cryoablation in NSCLC
Shanghai Chest Hospital
Phase 4 Not yet recruiting
NCT06580665 2024-08-30
Cryoablation with or Without Serplulimab in Treating Patients with Stage I-IIA Non-small Cell Lung Cancer
Shanghai Chest Hospital
Phase NA Not yet recruiting
NCT06530784 2024-07-31
Cryoablation Combined With PD-1 Antibody and Bevacizumab for Hepatocellular Carcinoma
Shanghai Zhongshan Hospital
Phase 2 Not yet recruiting
NCT04713371 2024-05-09
A Phase 2 Trial for Patients With Metastatic Solid Cancer
Rampart Health, L.L.C.
Phase 2 Active not recruiting
NCT00110110 2024-04-17
Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma
The Hospital for Sick Children
Phase 2 Active not recruiting
NCT03290677 2024-03-18
Study of Core Needle Biopsy and Cryoablation of an Enlarging Tumor in Patients With Metastatic Lung Cancer and Metastatic Melanoma Receiving Post-progression Immune Checkpoint Inhibitor Therapy
Massachusetts General Hospital
Phase NA Completed
NCT06265350 2024-02-20
Cryoablation Combined With Cardonilizumab and Bevacizumab in Hepatocellular Carcinoma With Pulmonary Metastases
Sun Yat-sen University
Phase NA Recruiting
NCT04118166 2023-12-12
Ipilimumab + Nivolumab + Cryotherapy in Metastatic or Locally Advanced Soft Tissue Sarcoma
Stanford University
Phase 2 Completed
NCT05032079 2023-10-16
Subzero and Scorpion Trial
Larkin Community Hospital
Phase NA Withdrawn
NCT03986593 2023-07-05
Cryoablation of Bone Metastases From Endocrine Tumors
Instituto do Cancer do Estado de São Paulo
Phase NA Terminated
NCT05893056 2023-06-27
CASTLE-09
Fudan University
Phase 2 Unknown
NCT05897268 2023-06-27
CASTLE-10
Fudan University
Phase 2 Unknown
NCT00002997 2023-06-15
Cryosurgery in Treating Patients With Unresectable Liver Metastases From Colorectal Cancer
Eastern Cooperative Oncology Group
Phase 2 Completed
NCT03390413 2023-06-01
ROAST
Aarhus University Hospital
Phase NA Withdrawn