Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS)
Phase 2 Terminated
53 enrolled 13 charts
Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia
Phase 2 Terminated
5 enrolled
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
Phase 3 Terminated
167 enrolled
A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)
Phase 1/2 Terminated
9 enrolled 21 charts
Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients
Phase 2 Terminated
20 enrolled
UPCC 25406
Phase 1/2 Terminated
4 enrolled
A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia
Phase 1 Terminated
7 enrolled
ISAKIDS
Phase 2 Terminated
67 enrolled 25 charts
Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Phase 1/2 Terminated
4 enrolled 8 charts
Pinometostat With Standard Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and MLL Gene Rearrangement
Phase 1/2 Terminated
6 enrolled 13 charts
Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia
Phase 2 Terminated
11 enrolled 13 charts
DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Phase 1/2 Terminated
17 enrolled 15 charts
DEXAML-03
Phase 3 Terminated
73 enrolled
Study of Magrolimab Combinations in Participants With Myeloid Malignancies
Phase 2 Terminated
54 enrolled 26 charts
ENHANCE-2
Phase 3 Terminated
258 enrolled 25 charts
Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission
Phase 2 Terminated
5 enrolled 9 charts
A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors
Phase 1/2 Terminated
38 enrolled 34 charts
Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia
Phase 1 Terminated
19 enrolled
Natural Killer(NK) Cell Therapy for Acute Myeloid Leukemia
Phase 1 Terminated
3 enrolled
Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease
Phase 1 Terminated
1 enrolled
Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia
Phase 2 Terminated
4 enrolled 11 charts
CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease
Phase 2 Terminated
1 enrolled 6 charts
An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)
Phase 1/2 Terminated
70 enrolled
Study of Fosciclopirox in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Phase 1/2 Terminated
18 enrolled
EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)
Phase 1 Terminated
6 enrolled 11 charts
Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AML
Phase 3 Terminated
15 enrolled 11 charts
Continuous Infusion Chemotherapy (CI-CLAM) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Other High-Grade Myeloid Neoplasms
Phase 1 Terminated
13 enrolled
CPX-351 and Gemtuzumab Ozogamicin in Treating Patients With Relapsed Acute Myeloid Leukemia
Phase 1 Terminated
13 enrolled
Alvocidib Biomarker-driven Phase 2 AML Study
Phase 2 Terminated
104 enrolled 12 charts
Study of Alvocidib in Patients With Relapsed/Refractory AML Following Treatment With Venetoclax Combination Therapy
Phase 2 Terminated
11 enrolled 10 charts
A Study of the Tumor-targeting Human F16IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Very Low-dose Cytarabine in Patients With AML Relapse After Allogeneic Hematopoietic Stem Cell Transplantation
Phase 1 Terminated
30 enrolled
Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen
Phase 2 Terminated
17 enrolled 7 charts
Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma
Phase 2 Terminated
26 enrolled 11 charts
Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemia
Phase 1/2 Terminated
16 enrolled 13 charts
Efficacy/Safety of CPI-613 in Combination With HD Cyt. and Mito. vs HD Cyt. and Mito. in Older Patients With R/R AML
Phase 3 Terminated
200 enrolled 9 charts
Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Phase 2 Terminated
11 enrolled 6 charts
Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML
Phase 1 Terminated
8 enrolled
Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia
Phase 2 Terminated
6 enrolled 10 charts
Patients Receiving Induction With Liposomal Daunorubicin and Cytarabine (CPX-351) for Acute Myeloid Leukemia
Phase 4 Terminated
3 enrolled 10 charts
A Study Evaluating the Safety and Efficacy of Idasanutlin in Combination With Cytarabine and Daunorubicin in Patients Newly Diagnosed With Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission
Phase 1/2 Terminated
24 enrolled 14 charts
AflacLL1901 (CHOA-AML)
Phase 2 Terminated
8 enrolled 12 charts
Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma
Phase 2 Terminated
31 enrolled
Leukemia Stem Cell Detection in Acute Myeloid Leukemia
Phase 3 Terminated
18 enrolled 25 charts
Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL
Phase 1 Terminated
3 enrolled
Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid Leukemia
Phase 1/2 Terminated
20 enrolled 9 charts
MIRROS
Phase 3 Terminated
447 enrolled 24 charts
EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia
Phase 1 Terminated
3 enrolled
AML
Phase 3 Terminated
143 enrolled
Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia
Phase 2 Terminated
2 enrolled 7 charts
Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations
Phase 3 Terminated
9 enrolled