Clinical Trials Browser

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT00259740 2017-03-15

Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab

Phase 2 Completed

96 enrolled 7 charts

Plasma cell

Multiple Myeloma, Recurrence

NCT00091832 2014-01-28

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

Phase 2 Completed

255 enrolled 34 charts

Breast

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00104650 2011-01-24

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates

Phase 2 Completed

111 enrolled 20 charts

Plasma cell

Multiple Myeloma

Clinical Trials

Denosumab Strategy for Liver Cancer With Bone Metastases

DICE

TRIDENT

Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma

A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency

Denosumab for Smoldering Multiple Myeloma

ZAMBONI

A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

KEYNOTE-E86

DEFENCE

An Exploratory Study of Tislelizumab in Combination with Chemotherapy in Immuno-experienced Patients with EGFR/ALK/ROS1-negative Advanced NSCLC in the Second-line Setting

Dmab

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

KEYPAD

Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

LENVOS

Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases

Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

GeparX

REDUCE

PERIDENO

Pilot Study to Evaluate the Impact of Denosumab on Disseminated Tumor Cells (DTC) in Patients With Early Stage Breast Cancer

Denosumab for Breast Cancer With Bone Mets

Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases

Denosumab in Subjects With Giant Cell Rich Tumors of Bone

D-Beyond

Denosumab in Treating Patients With ER and/or PR Positive, HER2 Negative Metastatic Breast Cancer With Bone Metastases and Detectable Circulating Tumor Cells

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates