Announcements Trials
Browse Landscape

Phase

Phase 2 33Phase 3 29Phase 4 6Phase EARLY_PHASE1 4Phase 1 4Phase 1/2 3

Status

Completed 2Active not recruiting 2Withdrawn 1Unknown 1

Sponsor Class

OTHER 3INDUSTRY 3

Study Type

Interventional 6

Sponsor

Cancer Type

Breast 3Genitourinary 1

Conditions

Breast Neoplasms 3Giant Cell Tumor of Bone 2Prostatic Neoplasms 1Osteoporotic Fractures 1Osteoporosis 1Neoplasm Metastasis 1Musculoskeletal Pain 1Bone Diseases 1Arthralgia 1

Interventions

Dexamethasone 56Metformin 50Cyclophosphamide 47Saline Solution 39Cytarabine 37Cisplatin 36Zoledronic Acid 34Letrozole 34Carboplatin 33Sodium Chloride 32Bupivacaine 31Docetaxel 30Bevacizumab 30Vincristine 29Methotrexate 29Fluorouracil 28Propofol 27Capecitabine 27Fentanyl 26Doxorubicin 26Rituximab 25Drug Therapy 25Dexmedetomidine 25Prednisone 23Paclitaxel 23Oxaliplatin 21Morphine 21Gemcitabine 21Radiotherapy 19Prednisolone 19

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

6 trials
RecentStart dateEnrollment
Phase 4 × Interventional × Denosumab × Clear all
NCT04549207 2026-04-07

Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer

Ottawa Hospital Research Institute

Phase 4 Active not recruiting
240 enrolled
Breast

Breast Neoplasms

NCT04586660 2025-10-01

Study of XGEVA® (Denosumab) in Chinese Adults and Skeletally Mature Adolescents With Giant Cell Tumor of the Bone

Amgen

Phase 4 Active not recruiting
36 enrolled

Giant Cell Tumor of Bone

NCT03301857 2024-05-20

Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004

Amgen

Phase 4 Completed
85 enrolled 13 charts

Giant Cell Tumor of Bone

NCT02721433 2020-12-02

REaCT-BTA

Ottawa Hospital Research Institute

Phase 4 Completed
263 enrolled
BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms

NCT03811509 2019-01-28

B-ABLE

Parc de Salut Mar

Phase 4 Unknown
1,000 enrolled
Breast

Breast Neoplasms, Osteoporosis, Arthralgia, Osteoporotic Fractures, Musculoskeletal Pain

NCT02101164 2015-02-18

Evaluate Time Associated With the Preparation & Administration of Denosumab/Pamidronate in Patients With Solid Tumors and Metastatic Bone Disease

Amgen

Phase 4 Withdrawn

Bone Diseases

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