Clinical Trials

1,779 enrolled 14 charts

LymphoidPlasma cell

Lymphoma, Multiple Myeloma, Spinal Cord Compression

NCT00680992 2022-09-22

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

535 enrolled 16 charts

Giant Cell Tumors, Neoplasms, Giant Cell Tumor of Bone

NCT05402865 2022-06-02

A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone

Completed

301 enrolled

Giant Cell Tumor of Bone

NCT03520231 2021-11-23

Study Comparing Denosumab With Standard Treatment in Urothelial Cancer Patients With Bone Metastases

6 enrolled

Urinary Bladder Neoplasms, Carcinoma, Transitional Cell, Kidney Neoplasms, Ureteral Neoplasms

NCT01951586 2021-10-25

Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer

226 enrolled 24 charts

Thoracic

Carcinoma, Non-Small-Cell Lung

NCT02366130 2021-10-07

Trial of Ra-223 Dichloride in Combination With Hormonal Therapy and Denosumab in the Treatment of Patients With Hormone-Positive Bone-Dominant Metastatic Breast Cancer

45 enrolled 7 charts

Breast Neoplasms

NCT03027557 2021-05-25

DENOCINA

46 enrolled 49 charts

Head & Neck

Parathyroid Neoplasms, Hyperparathyroidism, Primary

NCT04798326 2021-03-15

MW032

Phase 1 Completed

120 enrolled

Sarcoma

Bone Neoplasms

NCT01624766 2021-02-25

Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers

Phase 1 Completed

57 enrolled

Neoplasm Metastasis, Neoplasms, Recurrence

NCT02682693 2021-02-02

GeparX

780 enrolled

Phase EARLY_PHASE1 Completed

Carcinoma, Ductal, Breast, Inflammatory Breast Neoplasms

NCT02721433 2020-12-02

REaCT-BTA

Phase 4 Completed

263 enrolled

BreastGenitourinary

Breast Neoplasms, Neoplasm Metastasis, Prostatic Neoplasms

NCT02900469 2020-08-21

Presurgical Trial of Denosumab in Breast Cancer

44 enrolled

Breast Neoplasms

NCT01419717 2019-09-24

Open-Label Access Protocol of Denosumab for Subjects With Advanced Cancer

129 enrolled 10 charts

BreastGenitourinary

Breast Neoplasms, Neoplasms, Prostatic Neoplasms

NCT00838201 2018-10-18

Extension Study to Evaluate Long Term Safety of Denosumab in Subjects Undergoing ADT for Non-Metastatic Prostate Cancer

384 enrolled 8 charts

Carcinoma, Neoplasms, Prostatic Neoplasms

NCT00089661 2018-10-17

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Aromatase Inhibitor Therapy for Non-metastatic Breast Cancer

252 enrolled 13 charts

Bone Diseases, Metabolic, Breast Neoplasms

NCT00089674 2018-10-17

AMG 162 in the Treatment of Bone Loss in Subjects Undergoing Androgen-Deprivation Therapy for Non-metastatic Prostate Cancer

1,468 enrolled 24 charts

Prostatic Neoplasms

NCT00286091 2018-10-17

Study on Prolonging Bone Metastasis-Free Survival in Men With Hormone Refractory Prostate Cancer

1,435 enrolled 15 charts

Hormone Refractory Prostate Cancer

NCT00896454 2018-10-17

Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum Calcium

BreastGastrointestinalGenitourinaryHead & NeckLymphoidPlasma cellThoracic

33 enrolled 22 charts

Humoral Hypercalcemia Of Malignancy, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung, Colonic Neoplasms, Endocrine Gland Neoplasms, Head and Neck Neoplasms, Hodgkin Disease, Hypercalcemia, Kidney Neoplasms, Lung Neoplasms, Lymphoma, Lymphoma, Non-Hodgkin, Multiple Myeloma, Neoplasm Metastasis, Neoplasms, Parathyroid Neoplasms, Thyroid Neoplasms

NCT00980174 2018-10-17

Study to Compare the Efficacy and Safety of DenosumAb Versus Placebo in Males With Osteoporosis

242 enrolled 19 charts

Endocrine

Bone Diseases, Metabolic, Osteoporosis, Multiple Endocrine Neoplasia Type 1

NCT00321620 2018-08-29

Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

1,904 enrolled 15 charts

Fractures, Bone

NCT03415477 2018-01-30

Deno-ABC

Phase 1/2 Completed

6 enrolled

Fractures, Spontaneous, Neoplasms, Recurrence, Bone Cysts, Aneurysmal

NCT00925600 2017-05-30

Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss

769 enrolled 21 charts

Bone Diseases, Metabolic, Cataract, Neoplasms, Osteoporosis, Prostatic Neoplasms

NCT00259740 2017-03-15

Open-Label, Phase 2, Proof of Concept Study in Multiple Myeloma - Denosumab

96 enrolled 7 charts

Plasma cell

Multiple Myeloma, Recurrence

NCT01920568 2017-01-16

A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors

487 enrolled 13 charts

Fractures, Bone

NCT02996734 2016-12-22

GCTLIMBS

Completed

412 enrolled

Sarcoma

Bone Neoplasms, Giant Cell Tumors, Giant Cell Tumor of Bone

NCT01824342 2015-03-05

Denosumab for Prolonging Bone Metastasis-Free Survival in Men With Hormone-Refractory Prostate Cancer

18 enrolled 13 charts

Castrate-resistant Prostate Cancer

NCT00950911 2014-02-11

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

BreastGenitourinaryPlasma cell

35 enrolled 8 charts

Breast Neoplasms, Multiple Myeloma, Neoplasms, Prostatic Neoplasms

NCT00091832 2014-01-28

Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

255 enrolled 34 charts

Breast Neoplasms, Neoplasm Metastasis, Neoplasms

NCT00104650 2011-01-24

Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates