Clinical Trials

17 enrolled 11 charts

Dermatologic

Melanoma, Skin Neoplasms

NCT06378047 2026-02-09

Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer

Phase 1 Completed

2 enrolled

Pancreatic Neoplasms

NCT07328243 2026-01-09

IRE-TCLN

85 enrolled

Lymphatic Metastasis

NCT07306273 2025-12-29

IRE Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Phase 2 Recruiting

20 enrolled

Pancreatic Adenocarcinoma Locally Advanced

NCT06451445 2025-12-11

WIRED

100 enrolled

Prostatic Neoplasms

NCT03484299 2025-10-29

Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Phase 1 Recruiting

20 enrolled

Phase NA Not yet recruiting

Pancreatic Neoplasms

NCT07191548 2025-10-10

LIVERMET-IRE

50 enrolled

Phase NA Not yet recruiting

Carcinoma, Hepatocellular, Liver Diseases

NCT07192731 2025-10-10

LIVERHCC-IRE

50 enrolled

Carcinoma, Hepatocellular

NCT06205849 2025-07-25

Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer

Phase 1 Recruiting

18 enrolled

Pancreatic Neoplasms

NCT03603808 2025-07-16

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Phase EARLY_PHASE1 Completed

35 enrolled

Gynecologic

Squamous Intraepithelial Lesions, HIV Seropositivity

NCT05555342 2025-05-14

A Novel Method for Treating Lung Met w/Combo of Electric Fields & Rad Therapy: A Single-Arm

6 enrolled

Thoracic

Lung Neoplasms, Neoplasm Metastasis

NCT04276857 2025-05-13

SMART

27 enrolled

Locally Advanced Pancreatic Cancer

NCT04972097 2025-02-12

PRESERVE

121 enrolled

Prostatic Neoplasms

NCT05513443 2025-01-20

PRIS

184 enrolled

Prostatic Neoplasms

NCT04760327 2024-10-17

GynECT

Phase 2 Recruiting

Gynecological Cancers

NCT06185556 2024-08-23

COLDFIRE-III

Phase 2/3 Recruiting

78 enrolled

Phase 1/2 Not yet recruiting

Colorectal Neoplasms

NCT06047015 2024-08-09

Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer

12 enrolled

Liver Metastasis Colon Cancer

NCT03630640 2024-07-31

NIVOLEP

43 enrolled

Carcinoma, Hepatocellular

NCT05609656 2024-06-03

ELI

Phase 2 Terminated

4 enrolled

Colorectal Neoplasms

NCT05435053 2023-09-15

CHECKPOINT

Phase 2 Terminated

9 enrolled

Pancreatic Neoplasms

NCT03185013 2023-07-27

REVEAL 1

Phase 3 Completed

201 enrolled 23 charts

Gynecologic

Squamous Intraepithelial Lesions, Uterine Cervical Dysplasia

NCT02531425 2023-05-15

TNBC

Phase 1 Completed

10 enrolled

Breast

Triple Negative Breast Neoplasms

NCT03823131 2023-05-09

Optimizing Antitumor Immunity Using Plasmid Electroporation, Pembrolizumab, and Epacadostat

Phase 2 Terminated

14 enrolled 12 charts

Head & Neck

Squamous Cell Carcinoma of Head and Neck

NCT01939665 2022-12-20

PANFIRE

Phase 1/2 Completed

50 enrolled

Pancreatic Neoplasms

NCT02082782 2022-12-20

COLDFIRE-2

51 enrolled

Colorectal Liver Metastases

NCT02791503 2022-12-20

CROSSFIRE

74 enrolled

Pancreatic Neoplasms

NCT04612530 2022-12-20

PANFIRE-3 Trial: Assessing Safety and Efficacy of Irreversible Electroporation (IRE) + Nivolumab + CpG for Metastatic Pancreatic Cancer

Phase 1 Unknown

18 enrolled

Pancreatic Neoplasms

NCT05512663 2022-08-23

Safety and Efficacy Evaluation of Transperineal Irreversible Electroporation (IRE) of Anterior Prostate Cancer

Phase NA Unknown

10 enrolled

Prostatic Neoplasms

NCT03257150 2022-08-11

A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer

12 enrolled

Pancreatic Ductal Adenocarcinoma

NCT04717687 2022-07-13

HOPE

Phase NA Withdrawn

Cholangiocarcinoma

NCT04835402 2022-03-09

EPIC-1

Phase 2 Unknown

8 enrolled

Neoplasm Metastasis, Pancreatic Neoplasms

NCT05046262 2021-09-16

Calcium Electroporation for Basal Cell Carcinomas - Proof of Concept Study

Phase 3 Unknown

25 enrolled

Dermatologic

Carcinoma, Basal Cell

NCT02329106 2021-09-05

Percutaneous Irreversible Electroportion in Unresectable Liver Cancer Close to Diaphragmatic Dome

Liver Neoplasms

NCT02333773 2021-09-05

IRE

15 enrolled

Liver Neoplasms

NCT02335112 2021-09-05

IRE

15 enrolled

Head & Neck

Head and Neck Neoplasms

NCT02335827 2021-09-05

IRE

15 enrolled

NCT02425059 2021-09-05

Irreversible Electroporation(IRE) For Unresectable Rectal Neoplasms

Rectal Neoplasms

NCT02430597 2021-09-05

IRE

Hilus Pulmonary Neoplasms

NCT02430610 2021-09-05

IRE

Gynecologic

Uterine Cervical Neoplasms

NCT02430623 2021-09-05

IRE

Urinary Bladder Neoplasms

NCT02430636 2021-09-05

IRE

Stomach Neoplasms

NCT02430662 2021-09-05

IRE

Gallbladder Neoplasms

NCT02430675 2021-09-05

IRE

Head & Neck

Laryngeal Neoplasms

NCT02430688 2021-09-05

IRE

Extremities Neoplasms

NCT02430701 2021-09-05

IRE

Esophageal Neoplasms

NCT02430753 2021-09-05

IRE

Thoracic

Lung Neoplasms

NCT02430766 2021-09-05

IRE

Lymphatic Metastasis

NCT02430779 2021-09-05

IRE

Ureteral Neoplasms

NCT03337997 2021-05-06

A Pilot Study of IRE for Resectable Pancreatic Cancer

Phase NA Withdrawn