Clinical Trials

Multiple Myeloma

NCT03467386 2026-02-17

Total Marrow and Lymphoid Irradiation Before Donor Transplant and Cyclophosphamide in Treating Patients With Acute Myeloid Leukemia

Phase 1 Suspended

56 enrolled

Leukemia, Myeloid, Acute

NCT05799612 2026-02-13

Phase I Study of TH1 Dendritic Cell Immunotherapy for the Treatment of Cutaneous Angiosarcoma

Phase 1 Active not recruiting

Hemangiosarcoma

NCT04898894 2026-01-26

Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

37 enrolled

Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute

NCT05317403 2026-01-12

Venetoclax to Augment Epigenetic Modification and Chemotherapy

Phase 1 Recruiting

40 enrolled

Leukemia, Myeloid, Acute

NCT07052370 2025-12-31

TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies

Phase 1 Recruiting

30 enrolled

Phase 1 Not yet recruiting

Hematologic Neoplasms

NCT07278856 2025-12-12

Ruxolitinib in Combination With CHOP Chemotherapy for the Treatment of Untreated Nodal T-Follicular Helper Cell Lymphomas

20 enrolled

Lymphoid

Lymphoma, T-Cell

NCT03263936 2025-10-16

Epigenetic Reprogramming in Relapse/Refractory AML

37 enrolled 11 charts

Leukemia, Recurrence, Leukemia, Myeloid, Acute

NCT03107988 2025-09-15

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

65 enrolled 38 charts

Neuroblastoma

NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

25 enrolled

CNSGenitourinarySarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT04023669 2025-02-07

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

21 enrolled

Phase 1 Active not recruiting

Microphthalmia, Isolated, with Coloboma 5, Brain Neoplasms, Medulloblastoma, Central Nervous System Neoplasms

NCT04250051 2025-01-13

Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia

2 enrolled

MyeloidOther hematologic neoplasm

Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Myeloid, Acute

NCT02043847 2024-11-13

BMT-03

12 enrolled 12 charts

Multiple Myeloma, Recurrence, Disease Progression

NCT06007911 2024-08-13

Venetoclax-Navitoclax With Cladribine-based Salvage Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Leukemia, Myeloid, Acute

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

150 enrolled 9 charts

Neuroblastoma, Ganglioneuroblastoma

NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

68 enrolled

CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT00020371 2024-03-04

BMS-247550 in Treating Patients With Cancers That Have Not Responded to Previous Therapy

Neoplasms, Neutropenia

NCT02728531 2023-11-01

Bendamustine and Rituximab Alternating With Cytarabine and Rituximab for Untreated Mantle Cell Lymphoma

18 enrolled

Lymphoid

Lymphoma, Mantle-Cell

NCT03240861 2023-11-01

NYESO SCT

5 enrolled

NCT00562640 2023-09-15

Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)

12 enrolled 13 charts

Gynecologic

Carcinoma, Ovarian Epithelial, Fallopian Tube Neoplasms, Ovarian Neoplasms

NCT00003927 2023-07-05

Combination Chemotherapy, Amifostine, and Peripheral Stem Cell Transplantation in Treating Patients With Stage II, Stage III, or Stage IV Breast Cancer

15 enrolled

Breast

Breast Neoplasms

NCT00052884 2023-06-18

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

8 enrolled

Immunoglobulin Light-chain Amyloidosis, Multiple Myeloma, Neoplasms, Plasma Cell, Drug-Related Side Effects and Adverse Reactions

NCT05330377 2023-04-25

GM-CLAG in Relapsed/Refractory FLT3-mutated AML

Recurrence, Leukemia, Myeloid, Acute

NCT00005835 2023-04-10

BSO

31 enrolled

Neuroblastoma

NCT01019850 2023-04-10

N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma

27 enrolled

Neuroblastoma

NCT04584112 2023-03-15

A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer

83 enrolled

Breast

Triple Negative Breast Neoplasms

NCT02960646 2023-02-16

Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cell

11 enrolled

Anemia, Aplastic, Blast Crisis, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT04661852 2023-02-15

Cabozantinib With Topotecan-Cyclophosphamide

12 enrolled

Sarcoma, Ewing, Osteosarcoma

NCT03612466 2022-10-14

A Dose Finding Study of CycloSam® Combined With External Beam Radiotherapy

Neoplasms, Osteosarcoma

NCT02943733 2022-09-23

Safety of TAS-102 in Combination With Temozolomide for Metastatic Pancreatic NETs

18 enrolled

EndocrineNET

Neoplasms, Neuroectodermal Tumors, Primitive, Neuroendocrine Tumors

NCT03018223 2021-09-16

Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT

LymphoidMyeloidOther hematologic neoplasmPlasma cell

32 enrolled 12 charts

Graft vs Host Disease, Hodgkin Disease, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myelomonocytic, Chronic, Primary Myelofibrosis

NCT01787474 2021-06-21

Donor Natural Killer Cells in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

30 enrolled

Leukemia, Myeloid, Acute

NCT02392793 2021-02-09

Talazoparib Plus Irinotecan With or Without Temozolomide in Children With Refractory or Recurrent Solid Malignancies

43 enrolled

Other solid neoplasm

Childhood Solid Tumors

NCT02423915 2021-01-08

Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention

LymphoidOther hematologic neoplasm

5 enrolled

Graft vs Host Disease, Leukemia, Lymphoma

NCT02750254 2020-10-20

Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation

LymphoidMyeloidOther hematologic neoplasm

5 enrolled

Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01248923 2020-09-30

A Study of ARRY-520 and Bortezomib Plus Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma

Other hematologic neoplasmPlasma cell

55 enrolled

Leukemia, Plasma Cell, Multiple Myeloma, Paraproteinemias, Plasmacytoma

NCT00462358 2020-09-28

A Study of ARRY-520 in Patients With Advanced Cancer

41 enrolled

Other solid neoplasm

Advanced Solid Tumors

NCT00004114 2020-07-31

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Hematologic Cancer

DermatologicLymphoidMyeloidOther hematologic neoplasm

Burkitt Lymphoma, Hodgkin Disease, Leukemia, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Myelodysplastic Syndromes, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Acute, Leukemia, Myelomonocytic, Chronic, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

NCT00054236 2020-07-27

Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia

Classical hematologyLymphoidMyeloidOther hematologic neoplasmPlasma cellSarcoma

55 enrolled

Pdgfra-Associated Chronic Eosinophilic Leukemia, Congenital Abnormalities, Anemia, Refractory, with Excess of Blasts, Burkitt Lymphoma, Leukemia, Erythroblastic, Acute, Hodgkin Disease, Leukemia, Leukemia, Megakaryoblastic, Acute, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Polycythemia Vera, Recurrence, Thrombocythemia, Essential, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Leukemia, Neutrophilic, Chronic, Leukemia, Myeloid, Acute, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative, Dendritic Cell Sarcoma, Interdigitating, Primary Myelofibrosis

NCT03506802 2020-07-24

NYSCT MM

Multiple Myeloma

NCT00003060 2020-06-30

Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Metastatic Melanoma

6 enrolled

Dermatologic

Melanoma

NCT00002866 2020-04-01

Docetaxel and Epirubicin With and Without G-CSF in Treating Women With Metastatic Breast Cancer

50 enrolled

Breast

Breast Neoplasms, Neutropenia

NCT00498316 2020-02-28

Cord Blood Expansion on Mesenchymal Stem Cells

LymphoidMyeloidOther hematologic neoplasm

98 enrolled

Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00007813 2020-02-17

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors