Clinical Trials Browser

Phase 3 × Completed × Fluorouracil × Clear all

NCT01150045 2026-05-19

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery

Phase 3 Completed

2,527 enrolled 14 charts

Gastrointestinal

Colonic Neoplasms, Colorectal Neoplasms

NCT04083235 2026-04-20

NAPOLI 3

Phase 3 Completed

770 enrolled 13 charts 1 FDA

Gastrointestinal

Metastatic Adenocarcinoma of the Pancreas

NCT03221426 2026-03-09

KEYNOTE-585

Phase 3 Completed

1,007 enrolled 25 charts

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT04882241 2026-03-06

KEYNOTE-585

Phase 3 Completed

120 enrolled 17 charts

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT03675737 2026-02-27

KEYNOTE-859

Phase 3 Completed

1,579 enrolled 31 charts 1 FDA

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT01013649 2026-02-23

Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery

Phase 3 Completed

546 enrolled 29 charts

Gastrointestinal

Pancreatic Intraductal Neoplasms

NCT03143153 2026-02-17

CheckMate 648

Phase 3 Completed

970 enrolled 15 charts 1 FDA

Various Advanced Cancer

NCT03615326 2025-12-11

MK-3475-811

Phase 3 Completed

738 enrolled 22 charts 3 FDA

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT03358472 2025-12-03

Pembrolizumab Plus Epacadostat, Pembrolizumab Monotherapy, and the EXTREME Regimen in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (KEYNOTE-669/ECHO-304)

Phase 3 Completed

89 enrolled 14 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Squamous Cell Carcinoma of Head and Neck, Head and Neck Neoplasms

NCT01358877 2025-11-28

APHINITY

Phase 3 Completed

4,804 enrolled 45 charts 1 FDA

Breast Neoplasms

NCT02967289 2025-11-17

IROCAS

Phase 3 Completed

Gastrointestinal

Colonic Neoplasms, Neoplasms

NCT02872116 2025-08-07

CheckMate649

Phase 3 Completed

2,031 enrolled 19 charts 1 FDA

Gastrointestinal

Adenocarcinoma Of Esophagus, Stomach Neoplasms

NCT03783442 2025-07-29

A Study of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Phase 3 Completed

649 enrolled 22 charts

Gastrointestinal

Esophageal Squamous Cell Carcinoma

NCT02059499 2025-07-23

Imiquimod, Fluorouracil, or Observation in Treating HIV-Positive Patients With High-Grade Anal Squamous Skin Lesions

Phase 3 Completed

91 enrolled 26 charts

Squamous Intraepithelial Lesions, HIV Infections

NCT02358031 2025-07-18

MK-3475-048

Phase 3 Completed

882 enrolled 50 charts 1 FDA

Parkinson Disease 4, Autosomal Dominant Lewy Body, Head and Neck Neoplasms

NCT03206151 2025-05-23

CMAB009 Combined With FOLFIRI First-line Treatment in Patients With RAS/BRAF Wild-type, Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT03750669 2025-05-13

Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer

Phase 3 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT02934529 2025-04-16

AIO-KRK-0114

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT02162563 2025-02-06

CAIRO5

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT02578368 2024-11-12

FLOT5

Phase 3 Completed

Gastrointestinal

Stomach Neoplasms

NCT03941093 2024-11-05

LAPIS

Phase 3 Completed

284 enrolled 14 charts

Gastrointestinal

Pancreatic Cancer Non-resectable

NCT04456699 2024-10-29

LYNK-003

Phase 3 Completed

335 enrolled 19 charts

Gastrointestinal

Colorectal Neoplasms

NCT03189719 2024-10-15

KEYNOTE-590

Phase 3 Completed

749 enrolled 40 charts 1 FDA

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Esophageal Neoplasms

NCT02135419 2024-07-26

ANCHOR

Phase 3 Completed

4,446 enrolled 13 charts

GastrointestinalGynecologic

Squamous Intraepithelial Lesions, Acquired Immunodeficiency Syndrome, Anus Neoplasms, HIV Infections, Papillomavirus Infections

NCT00630032 2024-02-21

TavIx

Phase 3 Completed

762 enrolled 14 charts

Breast Neoplasms

NCT02928224 2023-12-21

BEACON CRC

Phase 3 Completed

702 enrolled 82 charts 1 FDA

Gastrointestinal

Colorectal Neoplasms

NCT02753127 2023-11-15

CanStem303C

Phase 3 Completed

1,253 enrolled 18 charts

Gastrointestinal

Colonic Diseases, Digestive System Diseases, Digestive System Neoplasms, Gastrointestinal Diseases, Gastrointestinal Neoplasms, Intestinal Diseases, Intestinal Neoplasms, Neoplasms, Neoplasms by Histologic Type, Neoplasms by Site, Neoplasms, Glandular and Epithelial, Rectal Diseases, Colorectal Neoplasms

NCT02394795 2023-11-01

PARADIGM

Phase 3 Completed

823 enrolled 20 charts

Gastrointestinal

Colorectal Neoplasms

NCT03748134 2023-10-24

Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 )

Phase 3 Completed

Gastrointestinal

Esophageal Squamous Cell Carcinoma, Carcinoma, Squamous Cell, Esophageal Diseases, Esophageal Neoplasms, Gastrointestinal Diseases, Neoplasms, Squamous Cell

NCT02741570 2023-09-21

CheckMate 651

Phase 3 Completed

947 enrolled 19 charts

Head and Neck Neoplasms

NCT00309478 2023-06-29

Randomized Study Comparing CMF and Goserelin + Tamoxifen in Premenopausal Receptor-positive Patients

Phase 3 Completed

Breast Neoplasms

NCT02494583 2023-04-13

MK-3475-062

Phase 3 Completed

763 enrolled 29 charts

Gastrointestinal

Parkinson Disease 4, Autosomal Dominant Lewy Body, Stomach Neoplasms

NCT00202774 2023-04-12

Safety and Efficacy Study of XELOX vs. Oxaliplatin+5-FU CI as First Line Treatment in Metastatic Colorectal Cancer

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01718873 2023-04-12

OBELICS

Phase 3 Completed

230 enrolled 12 charts

Gastrointestinal

Neoplasm Metastasis, Colorectal Neoplasms

NCT02940925 2023-04-12

TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma

Phase 3 Completed

Nasopharyngeal Carcinoma

NCT00121992 2023-04-04

Docetaxel, Doxorubicin (A), Cyclophosphamide (C) (TAC) vs 5-Fluorouracil, A, C (5FAC) Breast Cancer Adjuvant Treatment

Phase 3 Completed

1,060 enrolled 20 charts

Breast Neoplasms

NCT05078827 2023-03-14

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Phase 3 Completed

Keratosis, Actinic

NCT00129389 2023-03-07

FAC Versus FAC Plus Weekly Paclitaxel as Adjuvant Treatment of Node Negative High Risk Breast Cancer Patients

Phase 3 Completed

1,925 enrolled 19 charts

Breast Neoplasms

NCT00129922 2023-03-06

Fluorouracil, Epirubicin, and Cyclophosphamide Alone or Followed by Paclitaxel for Early Breast Cancer

Phase 3 Completed

Breast Neoplasms

NCT03365765 2023-02-14

mFOLFOX6 Chemotherapy With Apatinib as Postoperative Treatment in Stage IIIB or IIIC Colorectal Cancer

Phase 3 Completed

Apatinib

NCT03231722 2023-01-05

TRIPLETE

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT00642577 2022-12-22

A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Chinese Patients With Metastatic Colorectal Cancer.

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms

NCT01926197 2022-10-28

Phase 3 Study of FOLFIRINOX (mFFX) +/- SBRT in Locally Advanced Pancreatic Cancer

Phase 3 Completed

27 enrolled 15 charts

Gastrointestinal

Pancreatic Neoplasms

NCT00274937 2022-10-25

Radiation Therapy, Amifostine, and Chemotherapy in Treating Young Patients With Newly Diagnosed Nasopharyngeal Cancer

Phase 3 Completed

111 enrolled 11 charts

Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7

NCT03665441 2022-10-18

Trybeca-1

Phase 3 Completed

512 enrolled 19 charts

Neoplasms

NCT01726452 2022-09-30

NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

Phase 3 Completed

Gastrointestinal

Esophageal Neoplasms

NCT00087178 2022-08-11

Comparison of Two Combination Chemotherapy Regimens in Treating Women With Breast Cancer

Phase 3 Completed

2,722 enrolled 14 charts

Breast Neoplasms

NCT01966471 2022-06-14

A Study of Trastuzumab Emtansine (Kadcyla) Plus Pertuzumab (Perjeta) Following Anthracyclines in Comparison With Trastuzumab (Herceptin) Plus Pertuzumab and a Taxane Following Anthracyclines as Adjuvant Therapy in Participants With Operable HER2-Positive Primary Breast Cancer

Phase 3 Completed

1,846 enrolled 19 charts

Breast Neoplasms

NCT02625610 2022-06-09

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Phase 3 Completed

499 enrolled 22 charts

Neoplasm Metastasis, Neoplasms

NCT02383966 2022-05-13

CHANGE2

Phase 3 Completed

243 enrolled 17 charts

Squamous Cell Carcinoma of Head and Neck