Clinical Trials Browser

Interventional × Folic Acid × Clear all

NCT05096663 2026-05-18

Testing the Use of Combination Immunotherapy Treatment (N-803 [ALT-803] Plus Pembrolizumab) Against the Usual Treatment for Advanced Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)

Phase 2/3 Active not recruiting

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT03581773 2026-05-04

DARENCA4

Phase 2 Recruiting

Stomatitis, Mucositis

NCT04024254 2026-03-04

A Study of Serum Folate Levels in Patients Treated With Olaparib

Phase 4 Completed

10 enrolled 14 charts

BreastGynecologic

Breast Neoplasms, Folic Acid Deficiency, Ovarian Neoplasms

NCT06285357 2025-11-20

The Effect of the Association EGCG, Folic Acid and Vitamin B12 in Preventing the Persistence of HPV Infection.

Phase NA Recruiting

Papillomavirus Infections

NCT03564678 2025-09-05

Levocarnitine and Vitamin B Complex in Treating PEG-Asparaginase or Inotuzumab Ozogamicin-Induced Hyperbilirubinemia in Patients With Acute Lymphoblastic Leukemia

Phase 2 Terminated

10 enrolled 5 charts

LymphoidOther hematologic neoplasm

Hyperbilirubinemia, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03750669 2025-05-13

Sequential Use of AG and mFOLFIRINOX as Neoadjuvant Chemotherapy for Resectable Pancreatic Cancer

Phase 3 Completed

Gastrointestinal

Pancreatic Neoplasms

NCT05289908 2025-05-04

Intrathecal Pemetrexed for Leptomeningeal Metastasis

Phase 1/2 Completed

Meningeal Carcinomatosis

NCT04881851 2025-04-16

IALA

Phase NA Terminated

Polycystic Ovary Syndrome

NCT04786964 2025-04-02

CONTERNO

Phase 3 Terminated

25 enrolled 10 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Neoplasm Metastasis

NCT06774885 2025-01-14

ROLE OF FOLIC ACID IN THE MANAGEMENT OF ADJUVANT ENDOCRINE THERAPY-INDUCED HOT FLASHES IN BREAST CANCER PATIENTS

Phase 3 Not yet recruiting

Breast Neoplasms, Hot Flashes

NCT02578680 2024-09-20

MK-3475-189

Phase 3 Completed

616 enrolled 19 charts 1 FDA

Carcinoma, Non-Small-Cell Lung

NCT03950674 2024-06-10

MK-3475-189

Phase 3 Completed

40 enrolled 20 charts

Parkinson Disease 4, Autosomal Dominant Lewy Body, Carcinoma, Non-Small-Cell Lung

NCT06158932 2024-04-03

A Single Group Study to Evaluate the Effects of a Myo-Inositol and D-Chiro Inositol Supplement on Symptoms Associated With Polycystic Ovary Syndrome and Hormone Imbalance

Phase NA Completed

Polycystic Ovary Syndrome

NCT04062656 2024-03-12

IMAGINE

Phase 2 Unknown

Gastrointestinal

Stomach Neoplasms

NCT00002650 2023-06-22

High-Dose Folic Acid in Preventing Colorectal Cancer in Patients Who Have Had Polyps Surgically Removed

Phase 2 Completed

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms

NCT01328171 2023-06-15

VOLFI

Phase 2 Completed

Gastrointestinal

Colorectal Neoplasms

NCT05774964 2023-03-20

Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases

Phase 2 Unknown

Gastrointestinal

For Patients With Colorectal Cancer Liver Metastases Who Were Not Able to Curative Surgical Resection.Focused on the Treatment Effect With the Quintuple Method

NCT05720559 2023-02-09

Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection

Phase 2 Not yet recruiting

Gastrointestinal

Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer

NCT05625308 2022-12-22

Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions

Phase NA Completed

Papilloma

NCT04265534 2022-09-21

KEAPSAKE

Phase 2 Terminated

Carcinoma, Non-Small-Cell Lung

NCT05505006 2022-08-19

Management of Preoperative Anaemia in Surgical Oncology

Phase 4 Unknown

Classical hematology

Anemia, Neoplasms

NCT03626922 2022-06-10

Study of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer Patients

Phase 1 Unknown

Gastrointestinal

Colorectal Neoplasms

NCT05378919 2022-05-18

RECTUM2015

Phase 2 Recruiting

Gastrointestinal

Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

NCT05296369 2022-03-25

Folic Acid Interferes With Radiation Esophagitis

Phase NA Unknown

Lung Neoplasms

NCT00402883 2021-11-09

Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer

Phase 2 Terminated

5 enrolled 6 charts

Lung Neoplasms

NCT00998946 2021-11-05

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Phase 2 Completed

29 enrolled 8 charts

Recurrence, Lymphoma, B-Cell

NCT03598374 2021-09-30

IROP-1

Phase NA Unknown

Infertility, Female, Polycystic Ovary Syndrome

NCT00606502 2021-03-05

Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment

Phase 2 Completed

201 enrolled 12 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms, Smoking

NCT04645745 2021-01-14

Myo-inositol, Alpha-Lactalbumin and Folic Acid Treatment in PCOS

Phase NA Completed

Polycystic Ovary Syndrome, Hyperandrogenism

NCT03585738 2020-11-05

IPOSI-1

Phase NA Not yet recruiting

Polycystic Ovary Syndrome, Pre-Eclampsia, Diabetes, Gestational

NCT01555190 2020-07-24

Combination Therapy With Myo-inositol and Folic Acid Versus Myo-inositol Alone

Phase NA Completed

Hirsutism, Menstruation Disturbances, Polycystic Ovary Syndrome

NCT00272324 2020-03-13

Aspirin/Folate Prevention of Large Bowel Polyps

Phase 2/3 Completed

Gastrointestinal

Adenoma, Polyps, Colorectal Neoplasms, Adenomatous Polyps

NCT03242993 2020-02-28

[18F]-AZAFOL AS POSITRON EMISSION TOMOGRAPHY (PET) TRACER in FR Positive Cancer Imaging

Phase 1 Completed

GynecologicThoracic

Lung Neoplasms, Ovarian Neoplasms

NCT02302326 2020-02-26

PI12/1984

Phase NA Completed

Inflammation, Insulin Resistance, Polycystic Ovary Syndrome

NCT00481871 2020-01-07

Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies

Phase 1/2 Completed

119 enrolled 13 charts

LymphoidOther hematologic neoplasm

Hodgkin Disease, Immunoblastic Lymphadenopathy, Leukemia, Lymphoma, Lymphoma, Non-Hodgkin, Waldenstrom Macroglobulinemia, Recurrence, Lymphoma, B-Cell, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Lymphoma, Large-Cell, Anaplastic, Lymphoma, Extranodal NK-T-Cell

NCT01118624 2020-01-07

Study of Pralatrexate in Female Patients With Previously-treated Breast Cancer

Phase 2 Completed

22 enrolled 10 charts

Breast Neoplasms, Neoplasm Metastasis

NCT00554827 2020-01-03

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Phase 1 Completed

DermatologicLymphoid

Lymphoma, Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Lymphoma, T-Cell, Cutaneous

NCT01134341 2019-12-18

Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Phase 1 Completed

DermatologicLymphoid

Mycosis Fungoides, Recurrence, Sezary Syndrome, Lymphoma, T-Cell, Cutaneous, Lymphoma, Primary Cutaneous Anaplastic Large Cell

NCT00722553 2019-12-17

Study of Pralatrexate to Treat Advanced or Metastatic Relapsed Transitional Cell Carcinoma of the Urinary Bladder

Phase 2 Completed

30 enrolled 12 charts

Urinary Bladder Neoplasms, Carcinoma, Carcinoma, Transitional Cell, Neoplasm Metastasis, Recurrence

NCT00923273 2019-11-26

Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer

Phase 1/2 Terminated

42 enrolled 16 charts

Carcinoma, Non-Small-Cell Lung, Lung Neoplasms

NCT02106650 2019-11-20

Phase II Study of Folotyn With Leucovorin to Prevent/Reduce Mucositis in Patients With Hematological Malignancies

Phase 2 Completed

Lymphoma, T-Cell, Peripheral

NCT03349333 2019-10-01

A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCL

Phase 3 Completed

85 enrolled 26 charts

Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral

NCT01165021 2019-09-25

A Study of Pemetrexed/Cisplatin as Pre-operative Treatment of Early Stage Nonsquamous Non-Small Cell Lung Cancer

Phase 2 Completed

19 enrolled 14 charts

Carcinoma, Non-Small-Cell Lung

NCT03903952 2019-04-05

Can B12 and Folate Levels Predict HPV Penetration in Patients With ASCUS?

Phase NA Completed

Atypical Squamous Cells of the Cervix

NCT03101579 2019-03-19

Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer

Phase 1 Completed

Recurrence, Meningeal Carcinomatosis

NCT01999738 2019-02-07

Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors

Phase 1 Completed

Carcinoma, Non-Small-Cell Lung

NCT03011320 2019-02-07

An Exploratory Study of the Folic Acid-tubulysin Conjugate EC1456 in Ovarian Cancer Subjects Undergoing Surgery

Phase 1 Completed

Ovarian Neoplasms

NCT02344888 2019-01-08

Adding Prednisolone During Ovulation Induction With CC in Lean Women With CC Resistant PCOS

Phase 4 Unknown

Infertility, Polycystic Ovary Syndrome

NCT03306745 2018-09-06

Micronutrient Supplementation in PCO-syndrome

Phase NA Completed

Infertility, Female, Polycystic Ovary Syndrome

NCT03422289 2018-02-06

Improved Effects of MI Plus Alpha-LA in PCOS

Phase NA Completed

Anovulation, Infertility, Polycystic Ovary Syndrome